Sökning: "endothelin"

Visar resultat 16 - 20 av 116 avhandlingar innehållade ordet endothelin.

1. 16. Ion channels and electrical activity in vascular smooth muscle: Effects of calcium store depletion, cholesterol and cholesterol-lowering drugs

   Författare :Andreas Bergdahl; Kärlfysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; statins; endothelin; cholesterol; caveolae; smooth muscle; TRP; Ca2 channels; SOC;

   Sammanfattning : Smooth muscle cells (SMCs) in the vessel wall contract to regulate blood flow and pressure, a function essential for normal circulation through tissues. On the other hand, migration and proliferation of SMCs are important factors in vascular disease, such as atherosclerosis and restenosis following surgical dilatation. LÄS MER

3. 17. Modulation of retinal progenitors : A bird’s-eye view of retinal regeneration and disease

   Författare :Dardan Konjusha; Finn Hallböök; Rusty Lansford; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Developmental neurobiology; Retinoblastoma; MYCN; Cone photoreceptor; Nolz1; Endothelin; Müller cells;

   Sammanfattning : The cell populations of the retina and their intricate organization provide us with one of the most important senses – vision. All retinal cell populations are derived from a common progenitor pool as a result of tight regulation of proliferation, differentiation, dedifferentiation, and programmed cell death. LÄS MER

4. 18. Pulmonary hypertension. Clinical and pathophysiological studies

   Författare :Nedim Selimovic; Göteborgs universitet; []
   Nyckelord :Pulmonary hypertension; Echocardiography; Right heart catheterisation; Pulmonary vascular resistance; Pulmonary function tests; Lung transplantation; Mortality on the waiting list; Vascular remodelling; Growth substances; Inflammation; Endothelin;

   Sammanfattning : Pulmonary hypertension (PH) is a common abnormality, most often associated with various cardiopulmonary diseases. Pulmonary arterial hypertension (PAH) is a devastating pulmonary vascular disease characterised by the proliferation of endothelial, smooth-muscle cells and fibroblasts. LÄS MER

5. 19. Stroke, Sex and Vascular Receptor Changes in the Brain

   Författare :Hilda Ahnstedt; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endothelin receptors; Cerebral ischemia; sex; estrogen; progesterone; sex differences; human cerebral arteries; endothelin-1; angiotensin II; middle cerebral artery occlusion; extra-cellular signal regulated kinase 1 and 2;

   Sammanfattning : Stroke is a severe cerebrovascular disease in which the neuronal tissue and vasculature of the brain undergo ischemia-evoked alterations. We have demonstrated an increased expression of cerebrovascular contractile receptors in the brain. This is hypothesized to mitigate cerebral blood flow and exacerbate tissue damage after stroke. LÄS MER

7. 20. Endogenous Nitric Oxide Production and Pulmonary Blood Flow : during different experimental lung conditions

   Författare :Manja Nilsson; Filip Fredén; Kristina Hambraeus-Jonzon; Göran Hedenstierna; Eddie Weitzberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nitric oxide; pulmonary blood flow; endotoxin; nitric oxide inhalation; endothelin; hypercapnia; acidosis; lavage-induced lung injury; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Sammanfattning : Nitric oxide (NO) is an important regulator of pulmonary blood flow and attenuates hypoxic pulmonary vasoconstriction (HPV). Nitric oxide is synthesized enzymatically in a number of tissues, including the lungs, and can also be generated from reduction of nitrite during hypoxia and acidosis. LÄS MER