Sökning: "endothelin-1"

Visar resultat 11 - 15 av 68 avhandlingar innehållade ordet endothelin-1.

  1. 11. Circulating biomarkers in patients with abdominal aortic aneurysm

    Författare :Despina Flondell-Sité; Vaskulära sjukdomar - kliniska studier; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; matrix metalloproteinases; biomarkers; risk factors; fibrinolysis; coagulation; inflammation; Abdominal aortic aneurysm; statin; interleukin 6.; APC-PCI complex; serpine-1; endothelin-1;

    Sammanfattning : Abdominal aortic aneurysm (AAA) develops in 3-6% of the population over 65 years and affects mainly men. AAA has a complex etiology involving inflammation, proteolysis, fibrinolysis and coagulation. LÄS MER

  3. 12. Stroke, Sex and Vascular Receptor Changes in the Brain

    Författare :Hilda Ahnstedt; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endothelin receptors; Cerebral ischemia; sex; estrogen; progesterone; sex differences; human cerebral arteries; endothelin-1; angiotensin II; middle cerebral artery occlusion; extra-cellular signal regulated kinase 1 and 2;

    Sammanfattning : Stroke is a severe cerebrovascular disease in which the neuronal tissue and vasculature of the brain undergo ischemia-evoked alterations. We have demonstrated an increased expression of cerebrovascular contractile receptors in the brain. This is hypothesized to mitigate cerebral blood flow and exacerbate tissue damage after stroke. LÄS MER

  4. 13. Retinal Ischemia - A Vascular Perspective

    Författare :Frank Blixt; Lund Medicin; []
    Nyckelord :retinal ischemia; Endothelin 1; MEK ERK pathway; stroke;

    Sammanfattning : .... LÄS MER

  5. 14. Experimental Studies on the Regulation of Glomerular Filtration Barrier Permeability In Vivo. Intra- and intercellular signaling mechanisms

    Författare :Julia Dolinina; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerular filtration barrier; Nitric Oxide; Endothelin-1; Angiotensin II; TRPC5; TRPC6 channel;

    Sammanfattning : .... LÄS MER

  7. 15. Regulation of vascular function by fluid mechanical forces. Development of a new vascular experimental platform for integrative physiological and molecular biological studies of living conduit vessels

    Författare :Li-Ming Gan; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; perfusion model; endothelium; smooth muscle cells; shear stress; pressure; nitric oxide; endothelin-1; vascular endothelial growth factor; c-jun; c-fos; real-time PCR; NO probe.;

    Sammanfattning : The vascular endothelium is a multifunctional interface between blood flow and target organs and is continuously exposed to fluid mechanical forces such as shear stress, compressive, and tensile forces. Both in vivo and in vitro data indicate that biomechanical forces exert important modulating effects on key vascular functions. LÄS MER