Sökning: "endothelin receptors"
Visar resultat 21 - 25 av 41 avhandlingar innehållade orden endothelin receptors.
21. The effects of endothelin-1 in human adipose tissue
Sammanfattning : Obesity is a result of an imbalance between energy intake and energy expenditure ending in an excessive accumulation of body fat. Being overweight or obese increases the risk of death because of obesity related complications, e.g. insulin resistance, type 2 diabetes, cardiovascular diseases and some types of cancer. LÄS MER
22. Calcium calmodulin-dependent protein kinase signal transduction in cerebral arteries
Sammanfattning : Cerebral arteries participate actively in the response that follows an episode of cerebral ischemia in man and rat. It has been shown that the vascular endothelin receptor expression is increased in stroke and organ culture. LÄS MER
23. Cytokine induced airway hyperreactivity characterized in an in-vitro model of asthma
Sammanfattning : Asthma is a chronic disorder of the lower airways, characterized by inflammation and hyperreactivity. Pro-inflammatory cytokines like tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) are known to play important roles in the pathogenesis, but our knowledge how these cytokines contribute to the development of airway hyperreactivity is limited. LÄS MER
24. Receptor Upregulation and MAPK Activity in Arteries and Bronchi Following Secondhand Smoke Exposure
Sammanfattning : Cigarette smoking is a major risk factor for cardiovascular and respiratory diseases. Contractile receptor changes have been observed in several vascular diseases. The intracellular mitogen activated protein kinase (MAPK) signaling pathways are suggested to be associated with receptor upregulation. LÄS MER
25. Endothelin in the pulmonary circulation with special reference to hypoxic pulmonary vasoconstriction
Sammanfattning : A number of substances originating from the pulmonary endothelium have recently been found to be involved in the regulation of pulmonary vascular tone. Accumulating evidence suggests that endothelial dysfunction contributes to pulmonary hypertension, an important clinical problem often associated with hypoxemia. LÄS MER