Sökning: "endothelial function"
Visar resultat 16 - 20 av 402 avhandlingar innehållade orden endothelial function.
16. Endothelial activation and inflammation in the tumor microenvironment
Sammanfattning : Tumors are composed not only of malignant cells, but also of various types of normal cells, including vascular cells and infiltrating immune cells, which drive tumor development and progression. The tumor vasculature is abnormal and dysfunctional due to sustained tumor angiogenesis driven by high levels of pro-angiogenic factors. LÄS MER
17. Role of GLP-1 receptor agonists in endothelial function
Sammanfattning : BACKGROUND: The leading cause of death for patients suffering from type 2 diabetes is macrovascular disease. Endothelial dysfunction is one of the earliest events identified in the pathogenesis of atherosclerosis. Hence, there is a need for finding glucose-lowering agents that cause direct positive effects on vasculature in diabetic patients. LÄS MER
18. Endothelial function and dysfunction in coronary artery bypass grafting
Sammanfattning : The integrity of the endothelium is of importance for short- and long-term results following coronary artery bypass grafting (CABG). In this thesis different factors of the endothelial role in the regulation of vascular tone in relation to various current aspects of CABG have been investigated. LÄS MER
19. Properties of the glomerular endothelial cell surface layer in vitro and in vivo
Sammanfattning : A healthy kidney produces final urine that is practically devoid of proteins and other physiologically important solutes. Tremendous amounts of fluid are filtered every day through the glomerular filtration barrier which is the actual sieving site in the kidney. LÄS MER
20. The role of leptin in endothelial dysfunction and cardiovascular disease
Sammanfattning : Objective: Obesity has become the leading cause of mortality worldwide; however, the fundamental pathophysiology underlying this association remains unclear. The discovery of adipokines, i.e., cytokines produced by adipose cells (adipocytes), revealed that adipose tissue is a highly endocrine organ, thus opening new lines of investigation. LÄS MER