Sökning: "endothelial dysfunction"

Visar resultat 21 - 25 av 157 avhandlingar innehållade orden endothelial dysfunction.

  1. 21. Exploring signaling pathways in endothelial mechanotransduction

    Författare :Yumeng Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mechanotransduction, the process by which cells sense and convert mechanical forces from their surroundings, plays a pivotal role in cellular function. For vascular endothelial cells, coping with the continuous and significant shear stress caused by blood flow is essential for the stability of the circulatory system. LÄS MER

  3. 22. Neutrophil-induced endothelial barrier dysfunction in acute inflammation : mechanisms and therapeutic strategies

    Författare :Joel Rasmuson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The acute inflammatory response is characterized by recruitment of leukocytes and increased vascular permeability, resulting in the cardinal signs of inflammation; redness, heat, swelling, pain and loss of function. Permeability changes of the vascular wall are important in functional immune responses and host defense. LÄS MER

  4. 23. Biomarkers in Cardiovascular Dysautonomia: an Emerging Field

    Författare :Madeleine Johansson; Kardiovaskulär forskning - hypertoni; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; Cardiovascular autonomic dysfunction; Syncope; Orthostatic hypotension; Postural Orthostatic Tachycardia Syndrome; Cardiovascular disease; Autonomic dysfunction;

    Sammanfattning : Background: Cardiovascular autonomic dysfunction is a multifactorial disorder manifested as orthostatic hypotension (OH) and postural orthostatic tachycardia syndrome (POTS). OH has been associated with an increased risk of cardiovascular disease (CVD), and the underlying mechanisms are not fully understood and explored. LÄS MER

  5. 24. Reproductive and Metabolic Consequences of the Polycystic Ovarian Syndrome

    Författare :Miriam Hudecova; Inger Sundström Poromaa; Jan Holte; Matts Olovsson; Per Olof Janson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; polycystic ovarian syndrome; long-term follow-up; ovarian reserve; anti-Müllerian hormone; insulin sensitivity; early insuline response; impaired glucose tolerance; diabetes; endothelial function; endothelial-dependent vasodilation; Obstetrics and gynaecology; Obstetrik och gynekologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Polycystic ovary syndrome (PCOS) is a complex clinical condition characterized by hyperandrogenism and chronic oligo/anovulation. Infrequent ovulation and metabolic alterations in women with PCOS are associated with subfertility and probably increased miscarriage rates compared with normal fertile women. LÄS MER

  7. 25. The role of red blood cells in cardiac and endothelial dysfunction in cardiometabolic disease

    Författare :Tong Jiao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Cardiometabolic disease, which includes the combination of cardiovascular disease, especially coronary artery disease and type 2 diabetes (T2D), is a major health problem and cause of mortality worldwide. ST-elevation myocardial infarction (STEMI) occurs when coronary arteries are occluded and is regarded as a life-threatening disorder. LÄS MER