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Visar resultat 1 - 5 av 157 avhandlingar som matchar ovanstående sökkriterier.
1. Renal Dysfunction and Cardiovascular Disease
Sammanfattning : Kidney dysfunction increases cardiovascular disease (CVD) risk. The mechanisms for the risk increase seem to involve a combination of traditional and non-traditional CVD risk factors.We studied renal dysfunction as CVD and mortality risk factor in middle-aged men free from diabetes and CVD. LÄS MER
2. Endothelial cells : dysfunction and repair mechanisms
Sammanfattning : Endothelial cells (ECs) are crucial component of the normal vascular wall, providing an interface between the bloodstream and surrounding tissue of the blood vessel wall. Endothelial progenitors cells (EPCs) circulate in the blood and migrate to regions of the circulatory system with injured endothelium and ischemic tissues. LÄS MER
3. Vascular Interactions in Innate Immunity and Immunothrombosis: : Models of Endothelial Protection
Sammanfattning : The phenomenon known as immunothrombosis has garnered increased attention over the last few years. Much work has been done to characterize the cross talk between hemostasis and the innate immune system. LÄS MER
4. The role of leptin in endothelial dysfunction and cardiovascular disease
Sammanfattning : Objective: Obesity has become the leading cause of mortality worldwide; however, the fundamental pathophysiology underlying this association remains unclear. The discovery of adipokines, i.e., cytokines produced by adipose cells (adipocytes), revealed that adipose tissue is a highly endocrine organ, thus opening new lines of investigation. LÄS MER
5. Endothelial Barrier Dysfunction in Multiple Organ Injury. An Experimental Study in Rats
Sammanfattning : Multiple organ dysfunction syndrome (MODS) is still the leading cause of mortality in the surgical intensive care unit. The effect on among others endothelial barrier permeability, reticuloendothelial function, organ function and protease-antiprotease activities was studied following a variety of challenges, especially over-activation of macrophages induced by intraperitoneal administration of zymosan. LÄS MER