Sökning: "endostatin"

Visar resultat 6 - 10 av 13 avhandlingar innehållade ordet endostatin.

  1. 6. Interaction of Heparan Sulfate with Pro- and Anti-Angiogenic Proteins

    Författare :Maarten Vanwildemeersch; Dorothe Spillmann; Ulf Lindahl; Anders Aspberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparan sulfate; angiogenesis; fibroblast growth factors; endostatin; histidine-rich glycoprotein; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : Heparan sulfate (HS) is an unbranched and negatively charged polysaccharide of the glycosaminoglycan family, based on the repeated (GlcNAcα1-4GlcAβ1-4) disaccharide structure. The HS backbone is modified by epimerization and sulfation in various positions. LÄS MER

  3. 7. Angiogenesis regulation in hormone dependent breast- and ovarian cancer

    Författare :Christina Bendrik; Charlotta Dabrosin; Malin Sund; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Angiogenesis is a key event in tumor progression and a rate-limiting step in the establishment of a clinical cancer disease. The net balance of pro- and anti-angiogenesis mediators in the tissue dictates the angiogenic phenotype of a tumor. LÄS MER

  4. 8. Novel biomarkers for detection of early acute kidney injury, renal recovery and bacterial infections in critically ill patients

    Författare :Niklas Jonsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diagnosis of infection in the intensive care unit (ICU) is challenging because the signs and symptoms normally attributed to infection are quite common also in ICU patients without infection. This is a problem as delayed antibiotic therapy may increase the risk of organ failure and ultimately, death. LÄS MER

  5. 9. Properties of Endothelium and its Importance in Endogenous and Transplanted Islets of Langerhans

    Författare :Åsa Johansson; Per-Ola Carlsson; JanOve Sehlin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; islet transplantation; endothelial cells; engraftment; beta cells; Diabetology; Diabetologi; Medical Cell Biology; medicinsk cellbiologi;

    Sammanfattning : Transplantation of insulin producing cells is currently the only cure for type 1 diabetes. However, even though the Edmonton protocol markedly increased the success rate of pancreatic islet transplantation, the long term insulin independence is still very poor. An adequate engraftment is critical for islet graft survival and function. LÄS MER

  7. 10. Role of Thrombospondin-1 in Endogenous and Transplanted Pancreatic Islets

    Författare :Johan Olerud; Per-Ola Carlsson; Nils Welsh; Leif Jansson; Thierry Berney; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical cell biology; Medicinsk cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Type 1 diabetes mellitus is a severe life-long disease with a pronounced risk of developing secondary complications. One way to avoid the latter is to restore the fine tuning of blood glucose homeostasis by transplantation of pancreatic islets. LÄS MER