Sökning: "endoplasmic"

Visar resultat 1 - 5 av 191 avhandlingar innehållade ordet endoplasmic.

  1. 1. Haptoglobin: Biosynthesis and Evolution

    Författare :Krzysztof B. Wicher; Erik Fries; John W. M. Creemers; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; haptoglobin; cleavage; C1r-LP; evolution; vertebrate; endoplasmic; Golgi; complement; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Sammanfattning : Haptoglobin (Hp) is a serum protein known for its ability to form a tight complex with hemoglobin (Hb) and thereby inhibiting the oxidative activity of Hb. Mammalian Hp is synthesized as a precursor (proHp) that undergoes proteolytic cleavage by a previously unidentified enzyme in the endoplasmic reticulum (ER). LÄS MER

  3. 2. Endoplasmic Reticulum Dynamic Structural Changes in Neurons: The Fission-Fusion Phenomena

    Författare :Krzysztof Kucharz; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fragmentation; fission; endoplasmic reticulum; neurons; FRAP; primary cultures; organotypic slice cultures; in vivo; in situ; calcium; fusion; NMDA receptor; 2-photon microscopy; confocal microscopy;

    Sammanfattning : The endoplasmic reticulum (ER) is crucial for protein synthesis and protein maturation, is involved in cell stress and serves in neurons as the major intracellular Ca2+ store. Neuronal ER forms a continuous network of cisterns and tubules extending from soma to a subset of dendritic spines. LÄS MER

  4. 3. Endoplasmic reticulum function in dendrites and dendritic spines of hippocampal neurons

    Författare :Ai Na Ng; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endoplasmic reticulum; primary culture; dendritic spines; live cell imaging; STIM1; carbachol; store-operated calcium entry; 3; familial Alzheimer s disease; 5-dihyroxyphenyglycine;

    Sammanfattning : In the hippocampus, dendritic spines are compartmentalized postsynaptic micro-domains in the excitatory synapse. Subsets of bigger and mushroom-shaped hippocampal dendritic spines contain tubules and cisterns of endoplasmic reticulum (ER) that are connected to the soma and dendrites of the neuron. LÄS MER

  5. 4. Membrane glycoproteins of the endoplasmic reticulum : their existence, biosynthesis and incorporation into membranes

    Författare :Hans Svensson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  7. 5. Characterisation of the novel endoplasmic reticulum chaperone ERDJ5

    Författare :Paula Cunnea; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Endoplasmic reticulum; chaperone; unfolded protein response; protein folding; disease;

    Sammanfattning : Communication between cells depends to a large extent on interactions between secreted proteins and membrane receptors. Therefore their production and release must be strictly regulated. Proteins that are destined for the extracellular space assemble and fold in the endoplasmic reticulum (ER). LÄS MER