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Visar resultat 1 - 5 av 53 avhandlingar som matchar ovanstående sökkriterier.
1. Endoplasmic Reticulum Dynamic Structural Changes in Neurons: The Fission-Fusion Phenomena
Sammanfattning : The endoplasmic reticulum (ER) is crucial for protein synthesis and protein maturation, is involved in cell stress and serves in neurons as the major intracellular Ca2+ store. Neuronal ER forms a continuous network of cisterns and tubules extending from soma to a subset of dendritic spines. LÄS MER
2. Engineering the Secretory Pathway for Recombinant Protein Secretion in Saccharomyces cerevisiae
Sammanfattning : In the past few decades there has been an increasing demand of biopharmaceutical proteins in the market. Several types of cell factories are applied to produce different pharmaceutical proteins. LÄS MER
3. Characterisation of the novel endoplasmic reticulum chaperone ERDJ5
Sammanfattning : Communication between cells depends to a large extent on interactions between secreted proteins and membrane receptors. Therefore their production and release must be strictly regulated. Proteins that are destined for the extracellular space assemble and fold in the endoplasmic reticulum (ER). LÄS MER
4. Protein expression analysis of insulin producing cells exposed to endoplasmic reticulum stress
Sammanfattning : The prevalence of type 2 diabetes mellitus (T2DM) is increasing rapidly as a result of the obesity epidemic. T2DM develops in individuals who fails to compensate for increased demand of insulin. LÄS MER
5. Plant Calreticulins - isoforms, localization and function
Sammanfattning : Calreticulin (CRT) is an endoplasmic reticulum (ER)-located protein involved in quality control of newly synthesized proteins as well as in calcium homeostasis of the cell. Most of what is known about CRT arises from studies of mammalian systems. LÄS MER