Sökning: "endoglycosidase"

Hittade 5 avhandlingar innehållade ordet endoglycosidase.

  1. 1. Bacterial modulation of host glycosylation - in infection, biotechnology, and therapy

    Författare :Jonathan Sjögren; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgG; endoglycosidase; Streptococcus pyogenes; glycosylation; EndoS;

    Sammanfattning : A majority of the proteins of the immune system are glycosylated and the glycans of IgG are essential for its functionality. Bacteria display enzymes that modulate the glycans of the immune system to weaken the host defense and favor bacterial survival. LÄS MER

  3. 2. Streptococcus pyogenes secreted enzymes interacting with the human host

    Författare :Mattias Collin; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA fingerprinting; Streptococcus pyogenes; Clinical biology; immunoglobulins; Klinisk biologi; autoimmunity; endoglycosidase; cysteine proteinase; glycosylation;

    Sammanfattning : Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. LÄS MER

  4. 3. Enzymes involved in biosynthesis and degradation of heparin-related polysaccharides

    Författare :Dagmar Sandbäck Pikas; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparin; heparan sulphate; biosynthesis; N-deacetylase N-sulphotransferase; endoglycosidase; heparanase; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Sammanfattning : Heparin and heparan sulphate (HS) are structurally related polysaccharides of the glycosaminoglycan type. As the glycan moiety of proteoglycans, they exist covalently linked to various core proteins. LÄS MER

  5. 4. Bacterial antibody hydrolyzing enzymes – as bacterial virulence factors and biotechnological tools

    Författare :Eleni Bratanis; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunoglobulins; Immunomodulation; Antibody mediated immunity; Glycosylation; Bacterial virulence; Bacterial enzymes; Biotechnology; streptococcus pyogenes; Bdellovibrio bacteriovorus;

    Sammanfattning : Antibodies are an essential part of the human immune system, and antibody mediated immunity has been an area of interest for many researchers for almost a century. An accumulation of knowledge regarding antibody structure, glycosylation and receptor interactions has contributed to the current understanding of antibody mediated immunity. LÄS MER

  7. 5. On the immunopathogenesis of systemic lupus erythematosus - Immune complexes, type I interferon system, complement system and platelets

    Författare :Christian Lood; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; systemic lupus erythematosus; autoimmunity; rheumatology; immunology; cardiovascular disease;

    Sammanfattning : Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disorder characterized by inflammation in several organ systems. SLE patients have an impaired ability to clear dying cells which leads to the exposure of several nuclear antigens which might break self tolerance. LÄS MER