Sökning: "endogenous factors"
Visar resultat 1 - 5 av 315 avhandlingar innehållade orden endogenous factors.
1. Endogenous and exogenous factors affecting lipoprotein lipase activity
Sammanfattning : Individuals with high levels of plasma triglycerides are at high risk to develop cardiovascular disease (CVD), currently one of the major causes of death worldwide. Recent epidemiological studies show that loss-of-function mutations in the APOC3 gene lower plasma triglyceride levels and reduce the incidence of coronary artery disease. LÄS MER
2. Endocannabinoid metabolism : the impact of inflammatory factors and pharmacological inhibitors
Sammanfattning : The endocannabinoid (eCB) system is an endogenous signaling system consisting of ligands (referred to as endocannabinoids, eCBs), receptors and metabolic enzymes. The eCB system is involved in homeostatic control of a variety of biological functions such as neuronal signaling, mood, appetite and pathological conditions such as pain, inflammation and tumour progression. LÄS MER
3. Endogenous sex hormones and cardiometabolic risk factors – population-based studies within the Skaraborg Project
Sammanfattning : Cardiovascular diseases are the major contributors to mortality in Sweden and globally. Men have a higher incidence of cardiovascular diseases compared to women, until women reach the menopause. Levels of sex hormones might explain these sex differences beyond known differences in risk factors. LÄS MER
4. Firms and people in place : driving forces for regional growth
Sammanfattning : The aim of the thesis is to quantitatively study the driving forces and mechanisms for regional growth from an endogenous and exogenous perspective and reveal the most important factors contributing to regional growth, by focusing on three aspects: local labour market, the supply side and the demand side of the labour market. The thesis is designed to use Swedish micro register data to develop spatial models with higher spatial resolution. LÄS MER
5. Risk factors in ischemic stroke
Sammanfattning : Ischemic stroke is a complex disease in which environmental and genetic factors make about equal contributions to the etiology. However, knowledge regarding the molecular basis of the genetic influence and the impact of specific lifestyle factors is limited. LÄS MER