Sökning: "endocrine tumors"

Visar resultat 16 - 20 av 73 avhandlingar innehållade orden endocrine tumors.

  1. 16. Behind the scenes of thyroid tumors : underlying genetic mechanisms

    Författare :Jia Jing Lee; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Familial medullary thyroid cancer; follicular thyroid cancer; anaplastic thyroid cancer; CCND1; UBCH10; p16; RASSF1A; BRAF; array-CGH; tumor progression; global methylation; LINE-1; LUMA;

    Sammanfattning : Thyroid cancer is the most frequently observed malignancy involving endocrine tissues. This group of diseases is also the major cause of death related to neoplasia of the endocrine system. Tumors in the thyroid gland are common in the general population and the majority represents benign follicular adenoma (FTA). LÄS MER

  3. 17. Molecular studies of multiple endocrine neoplasia type 1 (MEN1)

    Författare :Shideh Khodaei-O'Brien; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :genetics; MEN1; cancer; tumor suppressor gene; cDNA selection; mutation; menin; ortholog; evolution; conservation; expression; RNA; protein; RT-PCR;

    Sammanfattning : Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized by tumors of the parathyroids, the endocrine pancreas and anterior pituitary. The MEN1 locus has been previously localized to chromosome 11q13 and subsequently a MEN1 minimum region was defined by a combination of linkage and tumor deletion studies. LÄS MER

  4. 18. Multiple endocrine neoplasia type 1 : clinical and molecular characterization

    Författare :Bin Tean Teh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEN1; PYGM; loss of heterozygosity; thymic carcinoid; HPT-JT; HRPT2; FIHP; familial acromegaly; tumor suppressor gene.;

    Sammanfattning : This thesis is based on clinicopathologic and genetic studies of MEN1 and MEN1-like syndromes. Linkage to the MENl locus in chromosome 11q13 was confirmed in the largest known MEN1 family and 5 Swedish MEN1 families. An accuracy of >99. LÄS MER

  5. 19. Desmoid tumors. New aspects on diagnostic procedures, treatment and outcome

    Författare :Mikael Dalén; Göteborgs universitet; []
    Nyckelord :desmoid; fibromatosis; surgery; radiotherapy; chemotherapy; statistics; imaging; studies; cytology; biopsy; pathology;

    Sammanfattning : Desmoid tumor (aggressive fibromatosis) is a rare, benign fibroblastic/myofibroblasticneoplasm that originates from musculoaponeurotic structures. It never metastasizes but locallygrows aggressively and infiltrates surrounding tissues. The treatment of choice has beensurgery. However, local recurrences are frequent. LÄS MER

  7. 20. Mangafodipir trisodium (MnDPDP)-enhanced magnetic resonance imaging of the liver and pancreas

    Författare :Chen Wang; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Liver; pancreas; neoplasms; metastases; endocrine tumor; MR imaging; contrast medium; mangafodipir trisodium; MnDPDP; manganese; Onkologi; Oncology; Onkologi; diagnostisk radiologi; Diagnostic Radiology;

    Sammanfattning : Contrast-enhanced magnetic resonance imaging (MRI) of the liver and pancreas is frequently performed to improve the sensitivity and specificity of lesion detection in these organs. The concept of using tissue-specific contrast media is to selectively enhance the normal parenchyma, but not lesions, so that the contrast between tumorous and normal tissue is increased, and lesion detectability improved. LÄS MER