Sökning: "endocrine tumors"

Visar resultat 1 - 5 av 65 avhandlingar innehållade orden endocrine tumors.

  1. 1. Genetic studies of endocrine abdominal tumors

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ola Hessman; Uppsala universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; MEN1; LOH; pancreatic endocrine tumors; midgut carcinoid; Smad4 DPC4; Kirurgi; MEDICINE Surgery; MEDICIN Kirurgi; Surgery; kirurgi;

    Sammanfattning : Pancreatic endocrine tumors (PETs) occur sporadically or in the familial multiple endocrine neoplasia type 1 (MEN1) syndrome, whereas midgut carcinoids are nonfamilial, malignant endocrine tumors of the intestine. For these tumor entities morphological criteria are of limited use for prognostic prediction and selection of treatment. LÄS MER

  2. 2. Genetic Aspects of Endocrine Tumorigenesis A Hunt for the Endocrine Neoplasia Gene

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Alberto Delgado Verdugo; Uppsala universitet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exome sequencing; SDHAF2; epigenetics; methylation; methylation array; Sanger sequencing; pheochromocytoma; SI-NETs; carcinoid; oncology; endocrine surgery; parathyroid; Genetics; Genetik; Kirurgi; Surgery;

    Sammanfattning : Endocrine tumors arise from endocrine glands. Most endocrine tumors are benign but malignant variants exist. Several endocrine neoplasms display loss of parts of chromosome 11 or 18, produce hormones and responds poorly to conventional chemotherapeutics. The multiple endocrine neoplasia syndromes are mainly confined to endocrine tumors. LÄS MER

  3. 3. Intraoperative scintigraphic detection of abdominal endocrine tumors : Development and evaluation of hand held gamma sensitive probes for¹¹¹In

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ulf Öhrvall; Uppsala universitet.; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Adrenocortical carcinoma; endocrine pancreatic tumors; mid-gut carcinoids; intraoperative gammadetection; octreotide; scintigraphy; Kirurgi; MEDICINE Surgery; MEDICIN Kirurgi; Surgery; kirurgi;

    Sammanfattning : Surgery of endocrine tumors benefit from accurate pre and- intraoperative localization methods,and scintigraphy has become an important contribution in this respect. In the present thesis therequisites for scintigraphic localization of abdominal endocrine tumors and new detectors forintraoperative gammadetection are evaluated. LÄS MER

  4. 4. Pancreatic Endocrine Tumors and GIST - Clinical Markers, Epidemiology and Treatment

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sara Ekeblad; Uppsala universitet.; [2007]
    Nyckelord :Medicine; Pancreatic endocrine tumor; Gastrointestinal stromal tumor; Neuroendocrine; Multiple endocrine neoplasia type 1; Prognostic factors; Temozolomide; TNM staging; O6-methylguanine DNA methyltransferase; Growth hormone secretagogue receptor; Ghrelin; Medicin;

    Sammanfattning : Pancreatic endocrine tumors and gastrointestinal stromal tumors are rare. Evidence regarding prognostic factors, and in the former also treatment, is scarce.We evaluated the survival and prognostic factors in a consecutive series of 324 patients with pancreatic endocrine tumors treated at a single institution. LÄS MER

  5. 5. Phospholipase C β3, and its role in endocrine tumorigenesis

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Peter Stålberg; Uppsala universitet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical sciences; Phospholipase C beta 3; endocrine tumors; in situ hybridization; transfection; tumorsuppressor; differential expression; gene targeting; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : The Phospholipase C β3 (PLCB3) gene is located on chromosome 11q13, in the vicinity of theMultiple Endocrine Neoplasia type 1 (MEN1) suppressor gene. PLCB3 has been implicated inendocrine tumorigenesis based on findings of low expression in endocrine tumors, and the probableexistence of other suppressor genes located at 11q13. LÄS MER