Sökning: "endocannabinoid"
Visar resultat 6 - 10 av 18 avhandlingar innehållade ordet endocannabinoid.
6. Molecular determinants of endocannabinoid-mediated brain development
Sammanfattning : The enchanting process of brain development entails a fragile and finite time window, throughout which biochemical imbalances and external insults can potentially affect developing neuronal circuits. Within the numerous exquisitely orchestrated events taking place in the foetal brain, axonal pathfinding is of paramount importance. LÄS MER
7. Neurodevelopmental Consequences of Exposure to Paracetamol (Acetaminophen) and Related Drugs : Experimental studies in mice
Sammanfattning : Paracetamol (acetaminophen) is the analgesic pharmaceutical most commonly used during pregnancy and early life. While therapeutic doses of paracetamol are considered harmless during these periods, recent findings in both humans and rodents suggest a link between developmental exposure to paracetamol and behavioral consequences later in life. LÄS MER
8. Brain-derived neurotrophic factor and endocannabinoid functions in gabaergic interneuron development
Sammanfattning : Formation of the cerebral cortex is controlled by tightly regulated processes: the proliferation and survival decisions of neural progenitors, radial and tangential migration of neuronal precursors, axon guidance and dendritic growth underpinning the formation of synapses. Patterning of the neocortex has been extensively studied and significant progress has been made in understanding the principles of cortical neuronal circuit formation. LÄS MER
9. Generation and selection of motor behaviors neural circuits and endocannabinoid modulation
Sammanfattning : The generation of basic motor behavior relies on the activation of spinal neuronal networks called central pattern generators (CPGs). Descending drive from higher brain areas activates the spinal CPG to generate motor behavior. In the face of changes in the environment, animals make constant motor behavioral selection. LÄS MER
10. Neuromodulation via endocannabinoids and nitric oxide in the lamprey spinal cord
Sammanfattning : The overall objective of this thesis is to increase our understanding of neural networks generating locomotion. These networks called Central Pattern Generators (CPG), are localized in the spinal cord and can generate the basic locomotor pattern in the absence of sensory or supraspinal inputs. LÄS MER