Sökning: "embryonic"

Visar resultat 1 - 5 av 655 avhandlingar innehållade ordet embryonic.

  1. 1. Human embryonic stem cells for bone engineering applications

    Författare :Giuseppe Maria de Peppo; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human skeleton; bone; bone defects; bone regeneration; regenerative medicine; tissue engineering; biomaterials; scaffold; biocoral; titanium; osseointegration bioreactor; human stem cells; embryonic stem cells; mesenchymal stem cells; embryonic-derived progenitors; osteogenic differentiation; mineralization; immune response; in vitro; in vivo;

    Sammanfattning : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. LÄS MER

  3. 2. Pluripotent Stem Cells of Embryonic Origin : Applications in Developmental Toxicology

    Författare :Måns Jergil; Lennart Dencker; Aldert Piersma; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Embryonic stem cell; Microarray; Toxicogenomics; Valproic acid; Developmental toxicology; Teratogenicity; Neural tube defects; Histone deacetylase inhibitor; In vitro toxicology; Toxicology; Toxikologi; Toxicology; Toxikologi;

    Sammanfattning : General toxicity evaluation and risk assessment for human exposure is essential when developing new pharmaceuticals and chemicals. Developmental toxicology is an important part of this risk assessment which consumes large resources and many laboratory animals. LÄS MER

  4. 3. Common mechanism for teratogenicity of antiepileptic drugs : Drug-induced embryonic arrhythmia and hypoxia-reoxygenation damage

    Författare :Faranak Azarbayjani; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Atiepileptik drugs; embryonic heart; arrhythmia; cleft palate; ROS; antioxidants; Ikr; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Toxicology; toxikologi;

    Sammanfattning : The Antiepilptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), tri- and dimethadione (TMD and DMD) are known teratogens having a common malformation pattern in human and animal studies. This thesis was designed chiefly to test a hypothesis correlating the teratogenicity of these AEDs to episodes of pharmacologically induced embryonic arrhythmia and hypoxia-reoxygenation damage. LÄS MER

  5. 4. Embryonic Mortality and Sex Ratios in the Tree Sparrow

    Författare :Magnus Svensson; Jan Ekman; Jacob Höglund; Kathryn Arnold; Uppsala universitet; []
    Nyckelord :Ecology; Hatching success; Embryonic mortality; Sex ratio; Density dependence; Parasites; Ekologi; Passer montanus;

    Sammanfattning : Tree sparrows (Passer montanus) have been studied in two areas in Sweden since 1997. At both sites, tree sparrow eggs had remarkably low hatching success. On average only 60% of the eggs hatched. Analyses have shown that this was caused by embryonic mortality, which was highly sex biased. LÄS MER

  7. 5. Phenotypic Specification of Striatal Progenitors; Evidence for both cell-autonomous and environmental control as studied by transplantation into the adult and developing rodent brain

    Författare :Martin Olsson; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; striatal projection neurons; striatal development; somatostatin; parvalbumin; neuronal differentiation; neural transplantation; medial ganglionic eminence; lateral ganglionic eminence; forebrain dvelopment; cholinergic; embryonic; thyroid transcription fa; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : The striatum is the major component of the ventral telencephalon and basal ganglia, involved in the processing of cortical information. The vast majority of the neuronal population in the striatum are striatal projection neurons, with connection to the globus pallidus and substantia nigra. LÄS MER