Sökning: "embryologi människa teratologi Utvecklingsbiologi ontogeny embryology human teratology Development"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden embryologi människa teratologi Utvecklingsbiologi ontogeny embryology human teratology Development.
1. Development of the Mouse Lateral Telencephalon
Sammanfattning : The telencephalon is the most rostral part of the vertebrate central nervous system and is comprised of a number of structures important for voluntary movements and higher cognitive processes. This thesis focuses on the genetic mechanisms that control development of a number of telencephalic structures: the olfactory bulb, the striatum as well as the lateral and basolateral nuclei of the amygdala. LÄS MER
2. Hypoxia and differentiation in human neuroblastoma cells
Sammanfattning : The childhood tumour neuroblastoma is derived from immature cells of the sympathetic nervous system, which have become arrested at different maturation stages. Neuroblastoma is a malignancy with a high degree of heterogeneity, and there is a correlation between a poor differentiation status and a more aggressive phenotype. LÄS MER
3. Studies on chondrocyte integrins and mechanical signaling
Sammanfattning : Integrins are a family of cell surface receptors known to bind matrix proteins and to mediate signals such as mechanical signals between the cell and the surrounding matrix. We have studied integrins that are expressed by chondrocytes, with specific focus on the integrins that interact with the cartilage matrix protein collagen type II. LÄS MER
4. Molecular specification of expanded forebrain neural stem and progenitor cells
Sammanfattning : The molecular specification of neural precursor cells has been suggested to be a progressive process, with a transition from an early requirement for extrinsic signals to intrinsic mechanisms. Thus, the cells in the nervous system acquire distinct fates in response to extrinsic signals, which activate repertoires of transcription factors in a region and cell type specific manner. LÄS MER
5. Structural and evolutionary studies of a lipocalin: the alpha1-microglobulin protein and its gene
Sammanfattning : a1-microglobulin is a small glycoprotein present in plasma and in tissues surrounding the gastrointestinal and respiratory tracts. a1-microglobulin is a member of the lipocalin protein family and exhibits several of the typical traits of a lipocalin; it binds an unknown ligand which causes the brown color of the protein, it forms complexes with various different proteins and there have been indications of the presence of a receptor for a1-microglobulin on T-lymphocytes. LÄS MER