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1. 1. Arterial Thrombosis in Factor V Leiden or Activated Protein C Resistance. Clinical and Experimental Studies

   Författare :Ellis Sampram; Malmö Klinisk koagulationsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Activated protein c resistance; Factor V Leiden mutation; thrombophilia; hypercoagulable state; Factor V Leiden mice; arterial thrombosis; venous thromboembolism; peripheral vascular reconstructions; peripheral vascular reconstruction occlusion;

   Sammanfattning : Abstract The last two decades has seen an avalanche of studies establishing Activated protein C (APC) resistance due to Factor V Leiden mutation as the most prevalent genetic risk factor, yet known, for venous thromboembolism. This has been documented in 20-60% of patients with deep vein thrombosis (DVT). LÄS MER