Sökning: "elin kimland"

Hittade 2 avhandlingar innehållade orden elin kimland.

1. 1. Drug treatment in children with focus on off-label drug use

   Författare :Elin Kimland; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Child; drug treatment; off-label; drug related problems; adverse drug reactions; drug labelling;

   Sammanfattning : There is a lack of paediatric documentation concerning efficacy and safety of many drugs, which contribute to drug use outside the terms of the product license (off-label). In the present thesis, four studies (I-IV), using different settings and design to evaluate pharmacological treatment in children, with focus on off-label drug use, is presented. LÄS MER

3. 2. Off-label drug treatment and related problems in children : a register-based investigation

   Författare :Elin Kimland; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Child; drug therapy; drug labelling; off-label; drug information services; adverse drug reactions; prescription drugs; drug related problems;

   Sammanfattning : Introduction: There is a lack of pediatric documentation concerning efficacy and safety of many drugs, which may contribute to off-label drug treatment and increase the risk for adverse drug reactions (ADRs). Aims: To; (I) analyse the frequency and characteristics of pediatric off-label prescribing; (II) investigate frequency of off-label drug prescribing in pediatric ADR reports; (III) analyse drug related problems, the extent of off-label drug treatment in pediatric questions to a Drug Information Centre (DIC) and pediatric literature information adding to the labelling of the drug in DIC answers. LÄS MER