Sökning: "electrophiles"
Visar resultat 1 - 5 av 37 avhandlingar innehållade ordet electrophiles.
1. Thermo- and chemosensitive properties of Transient Receptor Potential Ankyrin 1 ion channels
Sammanfattning : The ability to sense and accommodate to an ever-changing environment is crucial for the survival of living organisms. Transient Receptor Potential (TRP) ion channels comprise a large superfamily of cation conducting membrane proteins that function as molecular sensors in diverse sensory processes including perception of light, taste, smell, sound, touch and temperature. LÄS MER
2. Reactivity of late transition metal complexes towards CO2 and other electrophiles
Sammanfattning : In times when dwindling energy resources is a major long-term problem for sustaining modern infrastructure and technologies, we need to focus on more enduring solutions. A key contribution to this achievement is catalysis. LÄS MER
3. Characterization of Membrane Proteins: From a gated plant aquaporin to animal ion channel receptors
Sammanfattning : Membrane proteins play several important roles in a cell. Among these proteins are aquaporins (AQPs) and transient receptor potential (TRP) ion channels that mediate water transport, temperature and noxious chemical sensation, respectively. LÄS MER
4. Method for measurement of exposure to electrophiles : Strategy for identification and exposure estimation using N-terminal haemoglobin adducts
Sammanfattning : We are exposed to many chemicals in our everyday life. Some of these chemicals could pose risks for our health. To reduce such risks, it is important to know what we are exposed to, how much, and how toxic the chemicals are. LÄS MER
5. Development of an adductomic approach to identify electrophiles in vivo through their hemoglobin adducts
Sammanfattning : Humans are exposed to electrophilically reactive compounds, both formed endogenously and from exogenous exposure. Such compounds could react and form stable reaction products, adducts, at nucleophilic sites in proteins and DNA. LÄS MER