Sökning: "efflux"

Visar resultat 6 - 10 av 159 avhandlingar innehållade ordet efflux.

  1. 6. Constraints on up-regulation of drug efflux in the evolution of ciprofloxacin resistance

    Författare :Lisa Praski Alzrigat; Diarmaid Hughes; Fernando Baquero; Uppsala universitet; []
    Nyckelord :ciprofloxacin; antibiotic resistance; drug efflux; bacterial fitness; marR; acrR; marA; experimental evolution; Mikrobiologi; Microbiology;

    Sammanfattning : The crucial role of antibiotics in modern medicine, in curing infections and enabling advanced medical procedures, is being threatened by the increasing frequency of resistant bacteria. Better understanding of the forces selecting resistance mutations could help develop strategies to optimize the use of antibiotics and slow the spread of resistance. LÄS MER

  3. 7. Model membranes for orientation and efflux studies

    Författare :Malin Ardhammar; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PNA; membrane orientation; linear dichroism; membrane penetration;

    Sammanfattning : .... LÄS MER

  4. 8. N-acetylaspartate in brain - studies on efflux and function

    Författare :Mattias Tranberg; Göteborgs universitet; []
    Nyckelord :N-acetylaspartate; Hippocampal slice cultures; HPLC; NMDA; Excitotoxicity; Volume regulation; Canavan disease;

    Sammanfattning : N-acetylaspartate (NAA) is an amino acid derivative present in high concentration in the brain. The function of NAA is still unsettled in spite of 50 years of research. The mainly neuronal synthesis and glial breakdown of NAA requires a well regulated neuronal efflux and glial uptake. LÄS MER

  5. 9. Chloride transport and inflammation in cystic fibrosis airways

    Författare :Georgia Varelogianni; Godfried Roomans; Marie Johannesson; Ólafur Baldersson; Örebro universitet; []
    Nyckelord :Cystic fibrosis; CFTR; chloride efflux; N-acetylcysteine; ambroxol; duramycin; Nod-like receptors; cytokines; Medicin; Medicine;

    Sammanfattning : Cystic fibrosis (CF) is one of the most common lethal, autosomal recessive inherited diseases among Caucasians. It is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR), a chloride channel activated by cyclic AMP. LÄS MER

  7. 10. Apolipoprotein A-I in glucose metabolism and amyloidosis

    Författare :Oktawia Nilsson; Medicinsk proteinvetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloidosis; Apolipoprotein A-I; beta cell; cardiovascular disease; cholesterol efflux; diabetes; glucose metabolism; glycation; high-density lipoprotein; insulin secretion;

    Sammanfattning : The role of Apolipoprotein A-I (ApoA-I), the main protein component of HDL, in cholesterol transport and metabolism is well known and has been studied for more than four decades. More recently, ApoA-I protein has been shown to also have a positive role in glucose control by both stimulation of glucose uptake by muscles and by increasing glucose-stimulated pancreatic insulin secretion. LÄS MER