Sökning: "effects on workflow"
Visar resultat 6 - 10 av 32 avhandlingar innehållade orden effects on workflow.
6. FET fusion oncoproteins in sarcoma tumorigenesis - lnteractions with the SWI/SNF chromatin remodeling complex and epigenetic effects
Sammanfattning : The FET family of fusion oncoproteins containing the N-terminal of either FUS, EWSR1 or TAF15 together with a transcription factor partner is the characteristic oncogenic driver of more than 20 types of sarcoma and leukemia, including myxoid liposarcoma and Ewing sarcoma. The FET oncoproteins are thought to function as aberrant transcription factors, however, the exact oncogenic mechanism remains to be elucidated. LÄS MER
7. Characterizing cancer cell signaling at the protein level : from targeted to proteome and phosphoproteome‐wide analyses
Sammanfattning : Proteins are the effectors of cellular functions and the constituting elements of cellular signaling cascades. The ability to analyze the abundances and the dynamics of proteins is central to dissect cellular signaling and its effects on cell physiology. LÄS MER
8. Integrative Approaches in Shotgun Proteomics : From sample preparation to multifaceted data analysis
Sammanfattning : Bottom-up proteomics mass-spectrometry gives an opportunity to shed light on var-ious biological aspects/characteristics such as protein composition, its modifications,interactions, and dynamics. Its applications span a wide range of biological sciencesaiming to eventually answer fundamental disease related questions or evaluate drugperformance and predict adverse effects. LÄS MER
9. Image analysis of prostate cancer tissue biomarkers
Sammanfattning : Prostate cancer is the second most common cancer in men. In order to improve diagnosis and prognosis, new sensitive and specific biomarkers are needed. Tissue biomarkers carry expression and morphological information of the tissue where they are expressed. LÄS MER
10. Archaeological Challenges, Digital Possibilities : Digital Knowledge Development and Communication in Contract Archaeology
Sammanfattning : This research concerns the digitalisation of archaeology, with a focus on Swedish contract archaeology. The aim is to understand how the archaeological discipline relates to the change that digitalisation brings and human involvement in these processes. LÄS MER