Sökning: "eNOS"

Visar resultat 21 - 25 av 46 avhandlingar innehållade ordet eNOS.

  1. 21. The role and regulation of nitric oxide and oxidative stress in cardiometabolic disease : focus on preeclampsia

    Författare :Sarah McCann Haworth; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiovascular (CVD) and metabolic diseases account for significant morbidity and mortality. Over the last decades, despite significant research and clinical effort, their global prevalence is estimated to further increase. LÄS MER

  3. 22. Nitric oxide in cardiovascular and renal disease : role of organic nitrates, inorganic nitrate and red blood cells

    Författare :Zhengbing Zhuge; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : RATIONALE: Cardiovascular and renal disorders are major health problems, which are often co-existing. Mechanistically, these conditions can be attributed to endothelial dysfunction, a process coupled with reduced nitric oxide (NO) bioavailability. LÄS MER

  4. 23. Nitric oxide formation from inorganic nitrate and nitrate : contribution from eukaryotic and prokaryotic pathways

    Författare :Liyue Huang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nitric oxide (NO) is an essential signaling molecule that plays a central role in a broad range of physiological functions. Classically, NO is synthesized from L-arginine and molecular oxygen by NO synthases. Once formed, it is rapidly oxidized to nitrite and nitrate. LÄS MER

  5. 24. Vascular mechanisms in ovulation

    Författare :Kenrokuro Mitsube; Göteborgs universitet; []
    Nyckelord :angiotensin; blood flow; nitric oxide; ovary; ovulation; permeability; permselectivity; rat.;

    Sammanfattning : Ovulation is a unique biological process, which involves the degradation and rupture of healthy tissue of the ovarian follicle and the extrusion of the oocyte. This process is initiated by the preovulatory surge of luteinizing hormone (LH), which leads to the up-regulation of various intraovarian mediators. LÄS MER

  7. 25. Mediators of cervical ripening in preterm birth : experimental and clinical investigations

    Författare :Susanne Abelin Törnblom; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cervix; preterm; cervical ripening; cytokines; chemokines; cyclooxygenase COX ; prostaglandin dehydrogenase PGDH ; induction; labour; nitric oxide; PgE2-gel; pregnancy; preterm labour;

    Sammanfattning : Background: Preterm birth (PTB) is by far the leading worldwide cause of infant mortality and morbidity. Despite decades of research, the frequency of PTB has not decreased and the basic mechanisms initiating the onset of labour are still poorly understood. Vaginal preterm birth cannot take place without cervical softening and remodelling. LÄS MER