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Visar resultat 1 - 5 av 13 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Fibromodulin and Dystrophin in Atherosclerosis: Novel roles for extracellular matrix in plaque development

   Författare :Annelie Shami; Kärlväggsbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; fibromodulin; dystrophin; carotid artery; lipid accumulation; restenosis; plaque;

   Sammanfattning : Cardiovascular disease represents nearly half the cases of noncommunicable diseases worldwide and is the leading global cause of death. The main underlying cause is atherosclerosis, and in atherosclerotic plaque progression the structure, composition and integrity of a dynamic extracellular matrix (ECM) is one very important factor. LÄS MER

3. 2. Neuromuscular injuries and pharyngeal dysfunction in snorers and sleep apnea patients : a study on pathological changes in the human soft palate and its relationship with swallowing dysfunction

   Författare :Farhan Shah; Per Stål; Sture Forsgren; Diana Berggren; Eva Svanborg; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Axons; BDNF; desmin; dystrophin; obstructive sleep apnea; OSA; pharyngeal function; muscle; myopathy; neuropathy; Schwann cells; swallowing dysfunction; upper airway; Medical Cell Biology; medicinsk cellbiologi; oto-rhino-laryngologi; Oto-Rhino-Laryngology; patologi; Pathology; molecular cell biology; molekylär cellbiologi;

   Sammanfattning : Obstructive sleep apnea (OSA) is a prevalent progressive sleep disorder with serious negative health consequences. Although several risk factors such as obesity can make an individual vulnerable to develop OSA, the pathophysiological mechanism for the collapse of the upper airway is unclear. LÄS MER

4. 3. Evaluation of surgical methods for sleep apnea and snoring

   Författare :Thorbjörn Holmlund; Diana Berggren; Eva Levring Jäghagen; Karl Franklin; Sören Berg; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sleep apnea syndromes; adverse effects; mortality; radiofrequency; sham surgery; randomized controlled trial; daytime sleepiness; snoring; tonsillar hypertrophy; tonsillectomy; cytoskeleton; desmin; dystrophin; muscle fiber; palatopharyngeus; soft palate; uvula.; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

   Sammanfattning : Background: Snoring and obstructive sleep apnea (OSA) are both common disorders with a number of negative health effects. The safety and efficacy of treating snoring and OSA surgically have been questioned and there has been a lack of studies in the field. LÄS MER

5. 4. Challenging the mystique Connection. Deciphering cell-matrix interactions role in atherosclerosis and restenosis

   Författare :Vignesh Murugesan; Kärlväggsbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dystrophin glycoprotein complex; beta-sarcoglycan; dystrophin; Plaque; vascular smooth muscle cells; atherosclerosis; restenosis;

   Sammanfattning : Atherosclerosis is the underlying cause for myocardal infarction, stroke and peripheral arterial disease, collectively referred to as cardiovascular diseases. These represent the major cause of death globally. LÄS MER

7. 5. Proteomic strategies for blood biomarker development in rare dystrophinopathies

   Författare :Camilla Johansson; Cristina Al-Khalili Szigyarto; Ola Söderberg; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Duchenne muscular dystrophy; Becker muscular dystrophy; proteomics; affinity-proteomics; biomarkers; DIA-MS; SRM-MS; immunoassay; suspension bead arrays; Duchenne muskeldystrofi; Becker muskeldystrofi; proteomik; affinitetsproteomik; biomarkörer; DIA-MS; SRM-MS; immunoassay; suspension bead array; Biotechnology; Bioteknologi;

   Sammanfattning : Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are two rare genetic disorders of the family dystrophinopathy. They are both caused by the lack of, or reduced production of, the protein dystrophin. LÄS MER