Sökning: "dyrager christine"

Hittade 4 avhandlingar innehållade orden dyrager christine.

  1. 1. Design and Synthesis of Chalcone and Chromone Derivatives as Novel Anticancer Agents

    Författare :Christine Dyrager; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chalcones; Chromones; Fluorescence; Fluorophore; Cellular imaging; Anticancer; Tubulin; Microtubule; Kinase inhibitors; p38; MEK1; Palladium-mediated reactions; Molecular modeling; Structure-Activity Relationships.;

    Sammanfattning : This thesis comprises the design and synthesis of chalcone and chromone derivatives and their use in various biological applications, particularly as anticancer agents (targeting proteins associated with cancer pathogenesis) and as potential fluorophores for live-cell imaging. Conveniently, all structures presented were synthesized from commercially available 2 ́-hydroxyacetophenones. LÄS MER

  3. 2. Development of fluorescent probes based on the benzothiadiazole scaffold

    Författare :Susanne Doloczki; Christine Dyrager; Eszter Borbas; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Fluorescent probes are valuable imaging tools for studying biological processes on a cellular level. While antibody-based fluorescence imaging typically requires fixation of cells, small-molecule fluorophores have the advantage that they can often be used for live-cell imaging. LÄS MER

  4. 3. Shining Light on Benzothiadiazoles and Indolines : Photophysical Properties and Cancer Cell Imaging

    Författare :Susanne Doloczki; Christine Dyrager; Andrey Klymchenko; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : Fluorescent molecules, also called fluorophores, play an important role in life sciences. As crucial tools in fluorescence microscopy, they can be used to study biological processes on a cellular level, which is a fundamental aspect of cancer research. LÄS MER

  5. 4. Live long and phosphor : synthesis of new 2,1,3-benzothiadiazole based scaffolds and novel organo-Au(I) luminophores

    Författare :Mauricio Posada Urrutia; Christine Dyrager; Sascha Ott; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : 2,1,3-Benzothiadiazole (BTD) has arisen as a scaffold of interest to a variety of fields including materials chemistry and medicinal chemistry. It is utilized in the development of light emitting materials, solar-cells, and batteries. LÄS MER