Sökning: "dynamic structure discovery"
Visar resultat 1 - 5 av 20 avhandlingar innehållade orden dynamic structure discovery.
1. Dynamic Structure Discovery and Ion Transport in Liquid Battery Electrolytes
Sammanfattning : The lithium-ion battery (LIB), the realisation of which earned the Nobel Prize in Chemistry 2019, has since its 1991 commercialisation become the dominant energy storage technology first for cell phones and other mobile electronics, then for power tools and other domestic appliances, and currently for electric cars and other vehicles. However, many applications would still benefit from higher power and energy densities, longer life-lengths and safer batteries. LÄS MER
2. Organizing the early project phases for frequent innovation in hypercompetitive industries
Sammanfattning : This licentiate thesis contributes to the understanding of the early project phases and dynamic capabilities as key elements for frequent product innovation in the hypercompetitive pharmaceutical industry. The main purpose of the licentiate thesis is to investigate how organizations organize the early project phases of R&D in hypercompetitive environments for frequent innovation by utilizing a dynamic capabilities perspective. LÄS MER
3. Structural studies of drug targets and a drug metabolizing enzyme
Sammanfattning : The work presented in this thesis describes how structural information about a protein can be acquired, and how it can be used to answer scientific questions about proteins’ function, their dynamic behaviour and their interactions with other proteins or ligands.The catalytic function of the pyrimidine-degrading, drug metabolizing enzyme β-ureidopropionase (βUP) is dependent on the shift between oligomeric states. LÄS MER
4. Functional and structural characterizations of phytoplankton-bacteria interactions in response to environmental challenges
Sammanfattning : Microorganisms, such as phytoplankton and bacteria, make up ≈70% of aquatic biomass and contribute 50-85% of the oxygen in Earth’s atmosphere. The microbial loop concept and the discovery of the large diversity in microbial communities acknowledge that biotic interactions between microorganisms in addition to resource competition enable the recycling of energy and nutrients in aquatic food webs. LÄS MER
5. Insights into dynamic covalent chemistry for bioconjugation applications
Sammanfattning : Dynamic covalent chemistry (DCC) is currently exploited in several areas of biomedical applications such as in drug discovery, sensing, molecular separation, catalysis etc. Hydrazone and oxime chemistry have several advantages, such as mild reaction conditions, selectivity, efficiency, and biocompatibility and therefore, have the potential to be for bioconjugation applications. LÄS MER
