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  1. 1. Glycerol esters of butyric and valeric acids counteract diet-related disorders : Prevention of metabolic disturbances induced by high-fat intake

    Författare :Thao Duy Nguyen; Avdelningen för livsmedel och läkemedel; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; short-chain fatty acids; lipid metabolism; cholesterol; gut microbiota; high-fat diet; inflammation; succinic acid; intestinal permeability; tight junction proteins; gut-brain barrier; apolipoprotein E; rats;

    Sammanfattning : Short-chain fatty acids (SCFAs), gut metabolites formed from indigestible dietary components by the colonic microbiota, are associated with numerous health effects, and may be responsible for the beneficial effects, at least in part, associated with dietary fibre. High-fat diets are known to cause low-grade inflammation in the body, but SCFAs are suggested to counteract unfavourable effects induced by these types of diets. LÄS MER