Sökning: "duodenal ulcer"
Visar resultat 21 - 25 av 35 avhandlingar innehållade orden duodenal ulcer.
21. Characterization of antibodies against Helicobacter pylori
Sammanfattning : H. pylori is associated with the development of peptic ulcer, gastritis, and gastric cancer. Eradication of H. pylori by antibiotic treatment gives a healing of peptic ulcer and gastritis. LÄS MER
22. Neutrophil recruitment in H. pylori induced inflammation: characterization of regulatory factors
Sammanfattning : Helicobacter pylori, a bacterium colonizing the human gastric mucosa, is strongly associatedwith the development of gastric and duodenal ulcers, as well as gastric, adenocarcinoma.Virtually all infected individuals develop active chronic gastritis characterized by a continousinfiltration of neutrophils as well as mononuclear cells. LÄS MER
23. Pharmacodynamic Modelling of Irreversible and Reversible Gastric Proton Pump Inhibitors
Sammanfattning : Acid related diseases like GERD, duodenal-and gastric ulcers and H. Pylori-positive peptic ulcer disease are primarily managed by reducing gastric acidity. Irreversible proton pump inhibitors (PPIs) inhibit gastric acid secretion effectively throughout the day by irreversibly inhibiting the gastric proton pump, H+, K+-ATPase, in the parietal cells. LÄS MER
24. Persistent Helicobacter pylori infection and host response
Sammanfattning : Helicobacter pylori persistently colonizes the gastric mucosa of approximately one half of the world's population. Colonization always leads to chronic gastric inflammation, which may progress to peptic ulcer disease, gastric cancer or MALT lymphoma. The nature of H. pylori infection is determined by bacterial, host and environmental factors. LÄS MER
25. Mass spectrometry-based proteomic strategies applied to Helicobacter pylori. A Search for candidate vaccine antigens
Sammanfattning : This thesis describes the development and refinement of proteomic strategies and the application of these on the human gastric pathogen H. pylori. The purpose was to identify proteins, and in particular membrane proteins, as potential targets for vaccine development. LÄS MER