Sökning: "dss-induced"

Visar resultat 1 - 5 av 17 avhandlingar innehållade ordet dss-induced.

  1. 1. Dynamic changes in T cell compartments and new approaches in evaluating DSS induced and Gai2 deficient colitis

    Författare :Maria Fritsch Fredin; Göteborgs universitet; []
    Nyckelord :colitis; Gai2- - mice; dextran sodium sulfate; ex vivo cultures; micro-Computed Tomography; IEL; thymus; Inflammatory Bowel Disease;

    Sammanfattning : The overall aim of this thesis was to increase the understanding of the immunopathology of Inflammatory Bowel Disease (IBD). The first aim was to elucidate how the thymus and the gut epithelium were affected by colitis. The second aim was to investigate new ways of assessing and monitoring colitis. LÄS MER

  3. 2. Characteristics and Consequences of Thymic Involution in Inflammatory Bowel Disease. Experimental studies in G?i2-deficient and DSS-induced Colitis as well as in IBD patients

    Författare :Kristina Elgbratt; Göteborgs universitet; []
    Nyckelord :Inflammatory bowel diseaseInflammatory bowel disease; G?i2- - mice; dextran sodium sulfate; thymocytes; T cell receptor excision circles TRECs ; resent thymic emigrants;

    Sammanfattning : Characteristics and Consequences of Thymic Involution in Inflammatory Bowel Disease. Experimental studies in G?i2-deficient and DSS-induced Colitis as well as in IBD patients Kristina Elgbratt Department of Microbiology and Immunology, Institute of Biomedicine, The Sahlgrenska Academy, G?teborg University, G?teborg Sweden Inflammatory Bowel Disease (IBD) is a chronic relapsing inflammatory disorder of the gastrointestinal tract, comprising ulcerative colitis and Crohn?s disease. LÄS MER

  4. 3. Sensory and secretory responses to intestinal distension; implications for the pathophysiology of the irritable bowel syndrome

    Författare :Marie Larsson; Göteborgs universitet; []
    Nyckelord :irritable bowel syndrome; secretion; transmucosal potential difference; migrating motor complex; colorectal distension; visceral sensitivity; colitis; enteric nervous system; rat; mouse;

    Sammanfattning : Irritable bowel syndrome (IBS) is a common gut disorder, characterized by abdominal pain and/or discomfort associated with disturbed bowel habits. The pathophysiology of IBS is complex and still largely unknown, although visceral hypersensitivity is frequently associated with the disease. LÄS MER

  5. 4. Neuromuscular function in the normal and inflamed colon. An experimental study in rat

    Författare :Lars Börjesson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; dextran sulphate sodium; DMPP; enteric nervous system; McN-A-343; nitric oxide; non-adrenergic; rat; second messenger; smooth muscle; VIP;

    Sammanfattning : Neuromuscular function of the longitudinal muscle layer of distal colon was investigated in segments from normal rats and from rats with colitis induced by dextran sulphate sodium (DSS) at 3% for 3 or 7 days or 5% for 7 days. The study was performed in vitro, on spontaneous tone, or after precontraction. LÄS MER

  7. 5. Effects of Dietary Fibre and Probiotics on Hindgut Fermentation in Healthy Rats and in Rats with Dextran Sulphate Sodium-Induced Colitis and Colon Cancer

    Författare :Camilla Bränning; Avdelningen för livsmedel och läkemedel; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carboxylic acids; probiotics; short-chain fatty acids; hindgut fermentation; Colonic health; prebiotics; microbiota; dietary fibre;

    Sammanfattning : The importance of colonic fermentation has been realised during recent years as it has been found to be associated with colonic health and thus the overall health of the individual. The fermentation of dietary fibre and the addition of probiotics can have positive effects on the luminal environment and the colonic microbiota. LÄS MER