Sökning: "drug-release"

Visar resultat 1 - 5 av 77 avhandlingar innehållade ordet drug-release.

1. 1. Structure evolution of phase-separated EC/HPC films for controlled drug release

   Författare :Pierre Carmona; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electron microscopy; coarsening; cellulose; phase separation kinetics; drug delivery; phase separation mechanisms; porous film; biopolymer; controlled drug release; confocal laser scanning microscope; spin-coating.;

   Sammanfattning : Porous phase-separated ethylcellulose/hydroxypropylcellulose (EC/HPC) films are used to control drug transport out of pharmaceutical pellets. The drug transport rate is determined by the structure of the porous films that are formed as the water-soluble HPC leaches out. LÄS MER

3. 2. Preparation of Tablets from Reservoir Pellets with an Emphasis on the Compression Behaviour and Drug Release

   Författare :Åsa Tunón; Göran Alderborn; Michael E. Aulton; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; multiple unit tablets; extrusion-spheronisation; barrier-coating; modified drug release; pellet types; compaction; tablet properties; deformation; densification; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

   Sammanfattning : The preparation of multiple unit tablets was investigated in this thesis with the intention of gaining a deeper understanding of some of the factors that influence the properties of such tablets.Initially, three different types of pellets (drug, soft and disintegrant pellets) were combined as a model to investigate the ability of the mixture to form disintegrating tablets. LÄS MER

4. 3. Prolonged Drug Release from Gels, using Catanionic Mixtures

   Författare :Tobias Bramer; Katarina Edsman; Per Hansson; Stefan Ulvenlund; Uppsala universitet; []
   Nyckelord :Pharmaceutics; gel; catanionic; vesicle; micelle; controlled release; diffusion; surfactant; drug delivery; Galenisk farmaci;

   Sammanfattning : The use of catanionic drug-surfactant mixtures was proven to be an efficient novel method of obtaining prolonged drug release from gels. It was shown that various commonly used drug compounds are able to form catanionic mixtures together with oppositely charged surfactants. LÄS MER

5. 4. Quantitative 3D reconstruction of porous polymers using FIB-SEM tomography -correlating materials structures to properties of coatings for controlled drug release

   Författare :Cecilia Fager; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; tomography; controlled drug release; 3D; connectivity; insulating material; polymer film; soft material; focused ion beam; scanning electron microscopy;

   Sammanfattning : Porous networks are found in a wide range of different advanced and technologically important materials and influence the materials properties. The networks are active components in for example batteries, food and pharmaceuticals. The interconnectivity of a network strongly influences the transport properties. LÄS MER

7. 5. Catanionic Aggregates in Gels : Prolonged Drug Release and Potential Implications for Topical Use

   Författare :Noel Dew; Erik Björk; Stefan Ulvenlund; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Galenisk farmaci; Galenisk farmaci; Pharmaceutics;

   Sammanfattning : Gels are popular dosage forms.  This topical dosage form may be advantageous compared to oral or parenteral dosage forms. Favorable rheological or bioadhesive properties of gels might provide extended contact times at the site of administration compared to aqueous solutions. LÄS MER