Sökning: "drug regulations"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden drug regulations.

  1. 1. Disarming bacteria : a structure-based approach to design an anti-virulence drug against Listeria monocytogenes

    Författare :Melanie Oelker; A. Elisabeth Sauer-Eriksson; Fredrik Almqvist; Karina Persson; Tiziano Tuccinardi; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistances; anti-virulence drug; Listeria monocytogenes; virulence regulation; PrfA; structure-based drug design; ring-fused 2-pyridones; allosteric regulation; Biochemistry; biokemi; medicinal chemistry; läkemedelskemi; molekylär cellbiologi; molecular cell biology; medicinsk biokemi; Medical Biochemistry; molekylärbiologi; Molecular Biology;

    Sammanfattning : Antibiotic resistances are one of the biggest threats to global health and if we don’t change our behavior and way of using antibiotics we will end up in a ‘post-antibiotic era’, in which common infections and minor injuries can once kill again and up to 10 million deaths per year may occur by 2050. Therefore, there is a high need for new anti-bacterial drugs, especially of alternatives to existing antibiotics with already described resistances. LÄS MER

  2. 2. Giftets värde : Apotekares förståelse av opium i Sverige, 1870-1925

    Författare :Daniel Berg; Paulina del los Reyes; Ronny Pettersson; Göran Salmonsson; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; pharmaca; opiates; narcotics; apothecary; history of opium; history of pharmacy; history of poison regulations; history of drug regulations; economic history of Sweden; 19:th century; Georges Bataille; Ernesto Laclau; Chantal Mouffe; Michel Foucault; Fernand Braudel; farmaka; droger; gifter; narkotika; opium; morfin; opiater; apotek; droghistoria; apotekshistoria; Sverige; diskursanalys; ekonomisk historia; Georges Bataille; Ernesto Laclau; Chantal Mouffe; Michel Foucault; Fernand Braudel; ekonomisk historia; Economic History;

    Sammanfattning : Before the regulation of opium as a “narcotic” in Sweden in 1923, opium was not regulated for its intoxicating properties and was freely available. But not in any kind of shop. Opium was legally available only through the pharmacies. This thesis explores how this free availability of a narcotic was understood by its traders, the pharmacists. LÄS MER

  3. 3. Class I Ribonucleotide Reductases : overall activity regulation, oligomerization, and drug targeting

    Författare :Venkateswara Rao Jonna; Anders Hofer; Arne Holmgren; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribonucleotide reductase; GEMMA; Allosteric regulation; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Ribonucleotide reductase (RNR) is a key enzyme in the de novo biosynthesis and homeostatic maintenance of all four DNA building blocks by being able to make deoxyribonucleotides from the corresponding ribonucleotides. It is important for the cell to control the production of a balanced supply of the dNTPs to minimize misincorporations in DNA. LÄS MER

  4. 4. The quality of private pharmacy services in a province of Lao PDR : perceptions, practices and regulatory enforcements

    Författare :Lamphone Syhakhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Lao PDR; National Drug Policy Programme; quality; private pharmacy; drug sellers; Good Pharmacy Practice; indicators; inspection; regulatory intervention; knowledge;

    Sammanfattning : Aim: To study the practices of private pharmacies, the quality of drugs and the effectiveness of government regulations. To explore drug sellers' and consumers' knowledge and perceptions about drug quality. LÄS MER

  5. 5. Critical paediatric bioethics and the treatment of short stature : an interdisciplinary study

    Författare :Maria Cristina Murano; Kristin Zeiler; Patrice Bourdelais; Bjørn Hofmann; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; critical paediatric bioethics; growth hormone treatment; medicalisation; phenomenology of the body; critical disability studies; short stature; drug regulations;

    Sammanfattning : Several studies have argued that there is a correlation between short stature and negative experiences and characteristics, such as social discrimination, economic disadvantage, health problems (especially for men). The idea that short men have a disadvantage in social interactions and in partner choices is also widespread in popular culture and common knowledge. LÄS MER