Sökning: "drug monitoring"

Visar resultat 1 - 5 av 203 avhandlingar innehållade orden drug monitoring.

  1. 1. Therapeutic Drug Monitoring in Psychiatry : Some aspects of utility in clinical practice and research

    Författare :Maria Dolores Chermá Yeste; Finn Bengtsson; Johan Ahlner; Ylva Böttiger; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TDM; psychoactive drug; pharmacokinetics; pharmacogenetics; naturalistic; elderly; child; Clinical pharmacology; Klinisk farmakologi;

    Sammanfattning : Background and objectives: Several new psychoactive drugs for the treatment of psychiatric disorders have been introduced onto the market since the late 1980s. Basic aspects of pharmacodynamics and pharmacokinetics (PK) are investigated before approval for general prescription. LÄS MER

  3. 2. Rational drug treatment in the elderly : "To treat or not to treat"

    Författare :Inger Nordin Olsson; Peter Engfeldt; Sten Landahl; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Elderly; polypharmacy; drug evaluation; nursing process; monitoring; inappropriate prescribing; quality of life; patient participation; Vårdvetenskap; Nursing Science;

    Sammanfattning : The general aim of this thesis was to examine the effect of interventions on the usage of inappropriate and hazardous multi-medication in the elderly ≥75 years with ≥5 drugs.Methods: Paper I describes a cluster randomization of nursing homes, the outcomes were; number of drugs, health status and evaluations. LÄS MER

  4. 3. Bioelectronic Devices for Targeted Drug Delivery and Monitoring of Microbial Electrogenesis

    Författare :Arghyamalya Roy; Daniel T Simon; Klas Tybrandt; Christopher Proctor; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Electrophoresis; Extracellular Electron Transfer EET ; Ion Exchange Membranes IEM ; Drug Delivery; Bupivacaine; Chronic Neuropathic Pain; Microfabrication; Inkjet Printing; Organic Electrochemical Transistor OECT ; Fumarate; Shewanella oneidensis; Dorsal Root Ganglia DRG ; Organic Electronic Ion Pump OEIP ;

    Sammanfattning : Despite a range of pain therapies available in the market, 70% of patients report so-called “breakthrough pain”. Coupled with global issues like opioid crisis, there is a clear need for advanced therapies and technologies for pain management. LÄS MER

  5. 4. Modeling the Interaction Space of Biological Macromolecules: A Proteochemometric Approach : Applications for Drug Discovery and Development

    Författare :Aleksejs Kontijevskis; Jarl Wikberg; Jan Komorowski; Robert Glen; Uppsala universitet; []
    Nyckelord :Bioinformatics; proteochemometrics; bioinformatics; chemoinformatics; chemical space; QSAR; retroviral proteases; HIV-1; drug resistance; pharmacogenomics; cytochrome P450; GPCRs; melanocortin receptors; interactome; machine-learning; rough sets; Bioinformatik;

    Sammanfattning : Molecular interactions lie at the heart of myriad biological processes. Knowledge of molecular recognition processes and the ability to model and predict interactions of any biological molecule to any chemical compound are the key for better understanding of cell functions and discovery of more efficacious medicines. LÄS MER

  7. 5. Bioanalytical development for application in therapeutic drug monitoring : focus on drugs used in psychiatry

    Författare :Daniel Öhman; Olof Beck; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Introduction: Since the 1950s and onwards, many new psychoactive drugs have been successfully introduced in clinical practice. A common feature of these drugs is a profound metabolism before clearance from the body. LÄS MER