Sökning: "downstream analysis"

Visar resultat 1 - 5 av 299 avhandlingar innehållade orden downstream analysis.

  1. 1. Metabolic analysis of shikimic acid producing Escherichia coli

    Författare :Louise Johansson; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Kemiteknik och kemisk teknologi; Biokemi; metabolism; Chemical technology and engineering; transcriptome analysis; phosphorus-limitation; carbon-limitation; fed-batch; chemostat; batch; fermentation technology; Escherichia coli; shikimic acid; Biotechnology; Bioteknik; Metabolism; Biochemistry; principal component analysis; 2D-fluorescence spectrophotometry; metabolic flux analysis; carbon-rich;

    Sammanfattning : Shikimic acid production using recombinant E.coli has been developed during the past 15 years due to the increased demand of this product, primarily as a starting material for the anti-influensa medicine Tamiflu?. A detailed metabolic analysis of a shikimic acid producing E. LÄS MER

  2. 2. Capacitive Biosensor - A Tool for Ultrasensitive Analysis : Application in Clinical Analysis and Process Monitoring

    Författare :Kosin Teeparuksapun; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Capacitive Biosensor; Ultrasensitive Analysis; Clinical Analysis; Bioprocess Monitoring; Human Serum Albumin; HIV-1 p24; Host Cell Proteins; Protein A; Current Pulse;

    Sammanfattning : Increasing demands for highly sensitive, accurate, fast and portable analytical assays have led to the development of new analytical tools. The integration of highly specific biological sensing elements and appropriate transducers has enabled design of even more efficient biosensor devices for the detection of target substances. LÄS MER

  3. 3. Normalization and analysis of high-dimensional genomics data

    Författare :Mattias Landfors; Patrik Rydén; Rebecka Jörnsten; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; normalization; pre-processing; microarray; downstream analysis; evaluation; sensitivity; bias; genomics data; gene expression; spike-in data; ChIP-chip; Mathematical Statistics; matematisk statistik;

    Sammanfattning : In the middle of the 1990’s the microarray technology was introduced. The technology allowed for genome wide analysis of gene expression in one experiment. Since its introduction similar high through-put methods have been developed in other fields of molecular biology. LÄS MER

  4. 4. Modeling Antibody Aggregation in Downstream Processing

    Författare :Frida Ojala; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Antibody; Aggregation; Downstream processing; Size exclusion chromatography; Reversible reaction model; General rate model;

    Sammanfattning : Antibodies are part of the immune system where their purpose is to recognize and neutralize foreign species such as viruses and bacteria, thus preventing and curing infections. The trend of using antibodies in the treatment of, for example, cancer is increasing. LÄS MER

  5. 5. Computational Analysis of Gas Flow and Heat Transport Phenomena in Ducts Relevant for Fuel Cells

    Författare :Jinliang Yuan; Värmeöverföring; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Thermal engineering; applied thermodynamics; Termisk teknik; termodynamik; PEMFC.; SOFC; CFD; Duct; Transport Process; Fuel Cell; Heat Transfer; Gas Flow; Numerical Simulation; Analysis;

    Sammanfattning : The thesis concerns modeling, simulation and numerical analysis of heat and mass transport, and fluid flow in ducts of both solid oxide fuel cells (SOFCs) and proton exchange membrane fuel cells (PEMFCs). The unique fuel cell boundary conditions (thermal, mass) for the flow ducts in fuel cells are identified and applied. LÄS MER