Sökning: "dosing"

Visar resultat 21 - 25 av 156 avhandlingar innehållade ordet dosing.

  1. 21. Computerized provider order entry and patient safety : experiences from an Iranian teaching hospital

    Författare :Alireza Kazemi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Medical Order Entry Systems; Decision Support Systems; Clinical; Adverse Effects; Medication Errors; Infant; Newborn; Patient Safety; Iran;

    Sammanfattning : Background: Medication dosing errors may have grave consequences for neonatal patients. Computerized Physician Order Entry (CPOE) with dosing decision support functionalities has been effective in reducing these errors. However, the adoption rate is low. Physicians' resistance has been identified as a significant barrier. LÄS MER

  3. 22. From Penicillin Binding Proteins to Community Interventions : Mathematical and Statistical Models Related to Antibiotic Resistance

    Författare :Patricia Geli Rolfhamre; Åke Svensson; Mikael Andersson; Dan I. Andersson; Karl Ekdahl; Bruce R. Levin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistance; mathematical modeling; pharmacokinetics; pharmacodynamics; penicillin binding protein; postantibiotic effect; reversibility; selection; community intervention; Mathematical statistics; Matematisk statistik; matematisk statistik; Mathematical Statistics;

    Sammanfattning : Antibiotic resistance has become a major public health concern and mathematical models are important analytical tools for the understanding, evaluation and prediction of the resistance problem and related control strategies.The risk of emerging antibiotic resistance and selection has rarely been a concern in the design of antibiotic drug dosing regimens. LÄS MER

  4. 23. Pharmacokinetic and Pharmacodynamic Modeling of Antibiotics and Bacterial Drug Resistance

    Författare :Ami Fazlin Syed Mohamed; Lena Friberg; Teresa Dalla Costa; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; pharmacokinetics; pharmacodynamics; modeling; antibiotics; resistance; combination; Gram-negative bacteria; gentamicin; colistin; meropenem; newborn infants; critically ill patients; Infectious Diseases; Infektionssjukdomar; Pharmaceutical Science; Farmaceutisk vetenskap;

    Sammanfattning : Exposure to antibiotics is an important factor influencing the development of bacterial resistance.  In an era where very few new antibiotics are being developed, a strategy for the development of optimal dosing regimen and combination treatment that reduces the rate of resistance development and overcome existing resistance is of utmost importance. LÄS MER

  5. 24. Microsieving in municipal wastewater treatment : Chemically enhanced primary and tertiary treatment

    Författare :Janne Väänänen; Avdelningen för kemiteknik; []
    Nyckelord :coagulation; wastewater treatment; flocculation; microsieving; control; primary treatment; tertiary treatment; coagulation; control; flocculation; microsieving; municipal wastewater treatment; primary treatment; tertiary treatment;

    Sammanfattning : Municipal wastewater treatment plants are constantly forced to make improvements. The main objectives are to reduce energy consumption, to increase the treatment capacity and to improve the effluent water quality. Microsieves in combination with chemical pretreatment can potentially fulfil these objectives. LÄS MER

  7. 25. Garnishing the smorgasbord of pharmacometric methods

    Författare :Henrik Bjugård Nyberg; Andrew Hooker; Johannes Schropp; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; pharmacokinetics; saddle points; nonidentifiability; modelling and simulation; tuberculosis; ethionamide; bioequivalence; model-integrated evidence; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The smorgasbord of methods that we use within the field of pharmacometrics has developed steadily over several decades and is now a well-laid-out buffet. This thesis adds some garnish to the table in the form of small improvements to the handling of certain problems. LÄS MER