Sökning: "dosing"

Visar resultat 1 - 5 av 121 avhandlingar innehållade ordet dosing.

  1. 1. Bio-Inspired Urea Dosing and NOx Conversion : using a Biomimetic Effervescent Injector

    Detta är en avhandling från Department of Energy Sciences, Lund University

    Författare :Peter Larsson; Lunds universitet.; Lund University.; [2019-03-04]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bio-Inspired; Biomimetics; Bombardier Beetle; AdBlue; DEF; AUS-32; SCR; Exhaust After-treatment; Dosing; Nitrogen Oxides;

    Sammanfattning : Transport of people and freight on-road have a big impact on the total energy use in the world. The majority of these transports is propelled with diesel engines and the reason is simply that the diesel engine is better than the gasoline engine due to lower fuel consumption. But the cost of this is the increase in dangerous nitrogen oxides (NOx). LÄS MER

  2. 2. Estimation of Dosing Strategies for Individualisation

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Siv Jönsson; Uppsala universitet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Dosing strategy; Individualisation; Pharmacokinetic; Pharmacodynamic; Modeling; NONMEM; Decision making; Farmaceutisk biovetenskap; PHARMACY Biopharmacy; FARMACI Biofarmaci;

    Sammanfattning : To increase the proportion of patients with successful drug treatment, dose individualisation on the basis of one or several patient characteristics, a priori individualisation, and/or on the basis of feedback observations from the patient following an initial dose, a posteriori individualisation, is an option. Efficient tools in optimising individualised dosing strategies are population models describing pharmacokinetics (PK) and the relation between pharmacokinetics and pharmacodynamics (PK/PD). LÄS MER

  3. 3. Automating levodopa dosing schedules for Parkinson’s disease

    Detta är en avhandling från Borlänge : Dalarna University

    Författare :Ilias Thomas; Högskolan Dalarna.; [2019]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Parkinson’s disease; levodopa; symptom assessment; symptom management; dosing algorithms; wearable sensors; microtablets; continuous infusion; FLOAT - Flexibel levodopa-optimerings och individanpassningsteknik; FLOAT - Flexible Levodopa Optimizing Assistive Technology;

    Sammanfattning : Parkinson’s disease (PD) is the second most common neurodegenerative disease. Levodopa is mainly used to manage the motor symptoms of PD. However, disease progression and long-term use of levodopa cause reduced medication efficacy and side effects. When that happens, precise individualized dosing schedules are required. LÄS MER

  4. 4. Clinical impact of epoetins in the treatment of anemia with special emphasis on patients with lymphoid malignancies. dosing, iron supplementation and safety

    Detta är en avhandling från Umeå : Strålningsvetenskaper

    Författare :Michael Hedenus; Umeå universitet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anemia; cancer; lymphoproliferative malignancies; erythropoietin; intravenous iron; safety; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; Oncology; onkologi;

    Sammanfattning : The aim of this thesis was to determine the relevant dose of arbepoetin-alfa (DA) in patients with lymphoproliferative diseases (LPD) and chemotherapy induced anemia (CIA), to study the clinical impact of intravenous (IV) iron supplementation combined with epoetin beta treatment, to identify factors that might predict hemoglobin (Hb) response to treatment with epoetins and to investigate safety of DA.A dose-finding phase II study was able to assess a reasonable DA dose of 2. LÄS MER

  5. 5. Safety of Medication in Paediatrics

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Kristina Star; Uppsala universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; paediatrics; adverse drug reaction; drug-related problem; medication error; patient safety; individual case safety reports; pharmacovigilance; medication; nurses; health care personnel; dosage form; NSAID; dosing; prescription; antipsychotic medicines; postmarketing surveillance; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Background: In paediatrics, the limited documentation to guide medication, the lack of suitable dosage forms, and the continuous development in childhood present a scenario where safety of medication is a particular challenge.Aim: To explore reported adverse drug reactions (ADRs) and the challenges in prescribing and administering medicines in paediatrics, in order to identify and suggest areas needing international surveillance within medication safety and improvement in the clinical setting. LÄS MER