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Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Radiation Oncology Data and Modelling Side Effects after Radiation Therapy

   Författare :Caroline Olsson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; dose and side effect data; dose-volume response; fractionation effect; LQ model; sequential two-phase radiotherapy; head and neck cancer; parotid gland; xerostomia; pelvic radiotherapy; gynecological cancer; pubic bone; pain; data integration; xerostomia;

   Sammanfattning : Although modern radiation therapy techniques have the ability to conform the dose distribution of ionizing radiation tightly around the volume to be treated, unwanted irradiation to surrounding organs remains a problem. The probability of a side effect arising in the normal tissue of a patient after radiation therapy can be modelled by sigmoid mathematical functions known as normal tissue complication probability (NTCP) models. LÄS MER

3. 2. Towards eliminating pelvic bone pain after radiation therapy among long-term gynecological cancer survivors

   Författare :Ann-Charlotte Waldenström; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pelvic radiotherapy; gynecological cancer; pelvic bone pain; dose-volume response;

   Sammanfattning : Aim: To investigate the prevalence of self-reported symptoms after pelvic radiation therapy among long-term gynecological cancer survivors, with special focus on pelvic bone pain, how it affects the daily life of the women and the relationship to absorbed doses. Methods: In an unselected, population-based study, gynecological cancer survivors from the Gothenburg and Stockholm regions, treated with pelvic radiation therapy between 1991 and 2003, were compared with a non-radiation-treated control population. LÄS MER

4. 3. Towards better quality of life after radiation therapy by improved response modeling

   Författare :Eleftheria Alevronta; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: To improve the quality of life of radiotherapy cancer survivors we need to improve our knowledge of the dose, volume and time-response relations of radiotherapy induced late effects. Aims: The aim of the thesis was to investigate predictors for normal-tissue complications of head and neck, and gynecological radiotherapy using response modeling. LÄS MER

5. 4. Predicting Normal Tissue Complications after External Beam Radiation Therapy

   Författare :Caroline Olsson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NTCP; fractionation effects; radiobiological modelling; pubic bone pain;

   Sammanfattning : Although modern external beam radiation (EBRT) therapy has the ability to conform the dose tightly around the volume to be treated, unwanted irradiation to surrounding normal tissue is still a problem. The probability of a side effect arising in normal tissue after EBRT is commonly modelled by an s-shaped dose-volume response curve where dose or volume are plotted against response (i. LÄS MER

7. 5. Optimizing postoperative radiation therapy in prostate cancer: focus on side-effects, practical implementation and dose distribution

   Författare :Karin Braide; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostatacancer; Postoperativ strålbehandling; Side-effects;

   Sammanfattning : Optimizing postoperative radiotherapy in prostate cancer: focus on side effects, practical implementation and dose distribution Karin Braide, MD Department of Urology, Institute of Clincal Sciences Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden ABSTRACT We analyzed side-effects, pre-treatment bladder preparations and dose distribution to the rectum in four different cohorts of patients, treated with postoperative radiotherapy (PRT) in prostate cancer. Side-effects according to a self-reporting survey revealed rectal bleeding as a main result in a follow up time of 6. LÄS MER