Sökning: "dose fractionation"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden dose fractionation.

  1. 1. Cellular effects of ionizing radiation : Relevant for understanding cancer risk after medical and environmental radiation exposures

    Författare :Pamela Chiaka Akuwudike; Andrzej Wojcik; Lovisa Lundholm; Kerstin Borgmann; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation; DNA damage; radiation-induced carcinogenesis; second primary cancer; cisplatin chemoradiotherapy; dose fractionation; low dose; low dose rate; dose and dose rate effectiveness factor DDREF ; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Radiation-induced cancers are stochastic and delayed effects of exposure to ionizing radiation. The dose-response relationship for radiation-induced cancers at both low dose/low dose rates and high doses (doses encountered during radiotherapy) remains unclear. LÄS MER

  3. 2. Patient Outcomes after Radiotherapy of Prostate Cancer. Impact of Absorbed Dose and Treated Volume

    Författare :Elisabeth Rasmusson; LUCC: Lunds universitets cancercentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer diagnosis; radiotherapy; brachytherapy; external beam; Dose- response; side effects; erectile dysfunction; lymphedema; hip osteoarthritis; Fractionation;

    Sammanfattning : Abstract Backgound Prostate cancer is the most common form of cancer in men in Sweden. Radiotherapy, including external beam radiation therapy (EBRT) and brachytherapy (BT), is important treatment alternatives to surgery and active surveillance. LÄS MER

  4. 3. Searching for the optimal radiotherapy treatment time, dose and fractionation - the role of hypoxia and reoxygenation : A modelling study

    Författare :Emely Lindblom; Iuliana Toma-Dasu; Ingmar Lax; Ludvig Paul Muren; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hypoxia; Reoxygenation; SBRT; Fractionation; Medical Radiation Physics; medicinsk strålningsfysik;

    Sammanfattning : The search for the optimal choice of treatment time, dose and fractionation regimen is one of the major challenges in radiation therapy. Several aspects of the radiation response of tumours and normal tissues give different indications of how the parameters defining a fractionation schedule should be altered relative to each other which often results in contradictory conclusions. LÄS MER

  5. 4. Radiotherapy for head and neck cancer : costs and benefits of time, dose and volume

    Författare :Karin Söderström; Björn Zackrisson; Werner Dubrowsky; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiotherapy; head and neck cancer; adjuvant treatment; accelerated fractionation; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Sammanfattning : Background In the treatment of head and neck cancers (HNCs), radiotherapy (RT) has the advantage of organ preservation compared to surgery. However, treatment toxicities associated with RT can affect important functions for everyday life, both in the acute and late stage. LÄS MER

  7. 5. Radiation Oncology Data and Modelling Side Effects after Radiation Therapy

    Författare :Caroline Olsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; dose and side effect data; dose-volume response; fractionation effect; LQ model; sequential two-phase radiotherapy; head and neck cancer; parotid gland; xerostomia; pelvic radiotherapy; gynecological cancer; pubic bone; pain; data integration; xerostomia;

    Sammanfattning : Although modern radiation therapy techniques have the ability to conform the dose distribution of ionizing radiation tightly around the volume to be treated, unwanted irradiation to surrounding organs remains a problem. The probability of a side effect arising in the normal tissue of a patient after radiation therapy can be modelled by sigmoid mathematical functions known as normal tissue complication probability (NTCP) models. LÄS MER