Sökning: "dopamine D 2 receptors"
Visar resultat 11 - 14 av 14 avhandlingar innehållade orden dopamine D 2 receptors.
11. Neurotoxicity of methylmercury : analysis of molecular mechanisms and behavioral alterations
Sammanfattning : MethyImercury (MeHg) is a global pollutant that is toxic for the nervous system, especially during development. Contaminated fish is the main route of human exposure. Recent studies have indicated that neurological alterations in humans may occur even after exposure to fairly low levels of MeHg. LÄS MER
12. The pathophysiological roles of kynurenic acid and cytokines in psychiatric illness
Sammanfattning : Kynurenic acid is an astrocyte-derived tryptophan metabolite and a marker of neuroinflammation that antagonizes N-metyl-D-aspartate (NMDA) and α7 nicotinic acetylcholine receptors in the brain. Increased levels have been found in the cerebrospinal (CSF) and brains of patients with schizophrenia and experimental studies have shown that kynurenic acid bi-directionally influences dopaminergic neurotransmission. LÄS MER
13. The circuit and synaptic organization of the basal ganglia output : mechanistic insights on movement disorders and action control
Sammanfattning : Understanding the neural circuitry underlying movement is a neuroscientific challenge that promises to help refining currently available treatments for movement disorders. Key structures for movement and action control are the basal ganglia nuclei, whose complexity has only just started to be resolved. LÄS MER
14. On the association between panic disorder and autonomic regulation – With special focus on the roles of respiration and on the catechol-O-methyltransferase gene
Sammanfattning : Background and aims: Panic disorder is a psychiatric disorder characterized by sudden attacks of intense anxiety. It displays a lot of features suggesting that it may be associated with an underlying aberration in the autonomic regulation of heart activity and respiration: i) the attacks are often characterized by respiratory symptoms and symptoms from the heart, ii) the attacks can be elicited by respiratory stimulants, iii) between attacks, patients with panic disorder often display enhanced respiratory variability and reduced heart rate variability, and iv) patients with panic disorder display enhanced prevalence of respiratory disorders and enhanced mortality in cardiovascular disease. LÄS MER
