Sökning: "disease course"

Visar resultat 6 - 10 av 623 avhandlingar innehållade orden disease course.

1. 6. Immunopathology of Inflammatory Bowel Disease

   Författare :Mohammad Kadivar; Leukocyt migration; []
   Nyckelord :Inflammatory bowel disease IBD ; Crohn s disease; Ulcerative colitis; T cell; Monocyte; macrophage; Neutrophil; anti-TNFa treatment; IBD disease activity index;

   Sammanfattning : Inflammatory bowel disease (IBD) is a chronic inflammatory condition affecting the gastrointestinal tract, with a remitting and relapsing course. There are two main forms of IBD: Crohn’s disease (CD) and ulcerative colitis (UC). LÄS MER

3. 7. A life-course approach to chronic kidney disease : risks and consequences

   Författare :Per-Ola Sundin; Scott Montgomery; Katja Fall; Per Sjöström; Dorothea Nitsch; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic kidney disease; pneumonia; grip strength; creatinine; cystatin C; adolescence; life-course epidemiology; risk factor; mortality;

   Sammanfattning : Successful primary prevention of chronic kidney disease (CKD) relies on understanding the pathways leading to established disease, including how they extend over the life-course. Projects in this thesis examine risk factors for CKD and consequences of impaired kidney function from a life-course perspective using routinely collected health-data in Swedish registers and research cohort data from the United Kingdom. LÄS MER

4. 8. Vascular dementia - classification and clinical correlates

   Författare :Ulla Andin; Lund Psykiatri; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; psychosomatics; Psychiatry; clinical psychology; Medicine human and vertebrates ; falls; clinical course; hypertension; orthostatic hypotension; dizziness; cerebrovascular disease; Alzheimer?s disease; Neuropathological subgroups; cardiovascular disease; Psykiatri; klinisk psykologi; psykosomatik; Medicin människa och djur ;

   Sammanfattning : During the period (1976-1995) a total of 175 consecutive patients (m 88/f 87) with neuropathologically verified vascular dementia (VaD) were examined. 22 patients with pure Alzheimer's Disease (AD) were also studied. All patients were diagnosed and followed at the Department of Psychogeriatrics (Lund University Hospital). LÄS MER

5. 9. All that's mine I carry with me. Early life disease and adult health in Sweden during 250 years

   Författare :Martin Lindström; Ekonomisk-historiska institutionen; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Key words: early life; life course; infant mortality rate; nutrition; disease; airborne infectious diseases; socioeconomic differences; historical demography; 18th-21st centuries; Sweden.;

   Sammanfattning : The aim of this thesis is to study early life risk exposures in relation to adult health and mortality in Sweden during 250 years. A number of causal mechanisms by which exposure to diseases and stressful economic and social conditions early in life may lead to increased morbidity and mortality later in life are discussed (paper I). LÄS MER

7. 10. CRISPR/Cas9-based therapies and the role of astrocytes in Alzheimer’s disease and Parkinson’s disease

   Författare :Evangelos Konstantinidis; Martin Ingelsson; Anna Erlandsson; Vilmantas Giedraitis; Magnus Essand; Harald Steiner; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Parkinson s disease; gene editing; CRISPR Cas9; amyloid-beta; astrocytes; neurons; iPSCs; electrophysiology;

   Sammanfattning : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common neurodegenerative disorders. Whereas the AD brain features plaques of amyloid-beta (Aβ) and neurofibrillary tangles of tau, the PD brain is characterized by Lewy bodies and Lewy neurites containing α-synuclein (αSyn). LÄS MER