Sökning: "disease course"
Visar resultat 11 - 15 av 623 avhandlingar innehållade orden disease course.
11. Life-course influences on occurrence and outcome for stroke and coronary heart disease
Sammanfattning : Although typical clinical onset does not occur until adulthood, cardiovascular disease (CVD) may have a long natural history with accumulation of risks beginning in early life and continuing through childhood and into adolescence and adulthood. Therefore, it is important to adopt a life-course approach to explore accumulation of risks, as well as identifying age-defined windows of susceptibility, from early life to disease onset. LÄS MER
12. Gastroesophageal reflux disease - complications and prognostic aspects
Sammanfattning : This thesis investigates several aspects on gastroesophageal reflux disease (GERD) and associated complications as Barrett’s esophagus and esophageal adenocarcinoma. I. To clarify the natural course of GERD, a pH-metry verified cohort was re-evaluated after 20 years. The course of GERD may well be progressive. LÄS MER
13. Cardiovascular disease and diabetes or renal insufficiency : the risk of ischemic stroke and risk factor intervention
Sammanfattning : BackgroundIn patients with diabetes mellitus (DM) or chronic kidney disease (CKD), established cardiovascular disease (CVD) is associated with an increased risk of recurrent events and poor outcome. Ischemic stroke after an acute myocardial infarction (AMI) is a devastating event that carries high risks of decreased patient independence and death. LÄS MER
14. Predictors of disease onset and progression in early rheumatoid arthritis : A clinical, laboratory and radiological study
Sammanfattning : To diagnose rheumatoid arthritis (RA) during the early stages of the disease is often difficult. The disease course shows great inter-individual variation from mild, self-limiting to very severe destruc-tive disease with extra-articular manifestations. LÄS MER
15. Insomnia : Prevalence, longitudinal course and health consequences - a twelve year perspective
Sammanfattning : The aim of this thesis is to investigate different aspects of insomnia by following a middle-aged population over a twelve-year period. In the present series of studies insomnia is defined as a complaint of either difficulties initiating sleep (DIS), difficulties maintaining sleep (DMS) or early morning awakenings (EMA). LÄS MER