Sökning: "directed diversity-oriented synthesis"

Hittade 1 avhandling innehållade orden directed diversity-oriented synthesis.

  1. 1. Development of 2-Pyridone-based central fragments Affecting the aggregation of amyloid proteins

    Detta är en avhandling från Umeå, Sweden : Umeå universitet

    Författare :Magnus Sellstedt; Umeå universitet.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 2-pyridone; central fragment alteration; multi-component reactions; directed diversity-oriented synthesis; peptidomimetics; amyloid; protein aggregation; pilicide; curlicide; Biorganic Chemistry; bioorganisk kemi;

    Sammanfattning : There are many applications of small organic compounds, e.g. as drugs or as tools to study biological systems. Once a compound with interesting biological activity has been found, medicinal chemists typically synthesize small libraries of compounds with systematic differences to the initial “hit” compound. LÄS MER