Sökning: "dilated cardiomyopathy"
Visar resultat 16 - 20 av 34 avhandlingar innehållade orden dilated cardiomyopathy.
16. Importance of cardiac reserve for evaluation and prediction of cardiac function and morbidity assessed by low-dose dobutamine stress echocardiography
Sammanfattning : This thesis aimed to evaluate the cardiac reserves capacity to be used to predict treatment effects, sub clinical heart disease and to evaluate b1-adrenoceptor (AR) gene polymorphism (Ser49Gly). Studies were performed in patients with dilated cardiomyopathy, in rats (young, healthy, diabetic and hypertensive), in mice (immunized against the ?1AR) and in heart-transplanted patients. LÄS MER
17. Two new disorders of glycogen metabolism
Sammanfattning : Glycogen is a polymer of glucose and serves as a source of rapidly available energy. Glycogen synthesis is initiated by autoglucosylation of glycogenin. Two glycogenin genes, GYG1 and GYG2, encode the two isoforms glycogenin-1 and -2, respectively. LÄS MER
18. Genetic and pathophysiological study of desmin derangements in cardiac disorders
Sammanfattning : Desmin is a chief intermediate filament of skeletal and cardiac muscle. Its main function is to provide structural and functional integrity to the cell and to transmit tension along the myofibrils, protecting them from mechanical stress during contractionrelaxation process. LÄS MER
19. Investigating the pathological heart and its regenerative potential
Sammanfattning : Cardiovascular disease is a leading contributor to mortality the world over, affecting millions of people each year. This, combined with its associated monetary and societal costs, has made the investigation of the etiology and pathophysiology of CVD a scientific priority. LÄS MER
20. The importance of long axis function -an echocardiographic study with respect to ageing, response to treatment, prediction of survival and effect of warm water immersion
Sammanfattning : Echocardiographic M-mode measurement of atrioventricular plane displacement (AVPD) and determination of annular velocity with Tissue Doppler imaging (TDI) is a reliable method to gauge ventricular long axis function for quantification of myocardial contractility and relaxation. The aim of this thesis was to increase the understanding of the importance of long axis function with respect to ageing, response to pharmacological treatment, prediction of survival, and enhanced load condition caused by warm water immersion. LÄS MER