Avancerad sökning

Hittade 3 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Somatosensory dysfunctin in fibromyaligia : implications for pathophysiological mechanisms

    Författare :Eva Kosek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :allodynia; diffuse noxious inhibitory controls DNIC ; fibromyalgia; hyperesthesia; isometric contraction; pain modulation; pain inhibition; pressure algometry; quantitative sensory testing; sensitivity; sensitization; tourniquet test; v;

    Sammanfattning : Fibromyalgia is a chronic pain syndrome characterized by generalized pain, tenderness, disturbed sleep and pronounced fatigue. The pathophysiology is unknown but peripheral mechanisms (i.e., muscle ischemia) as well as central mechanisms (dysfunction in endogenous pain modulation) have been implicated. LÄS MER

  3. 2. Pain influences somatosensory perception : an experimental and clinical study

    Författare :Ann-Sofie Leffler; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Muscle pain; referred pain; hypoaesthesia; allodynia; musculoskeletal; pain; sensory abnormality; quantitative sensory testing; trapezius myalgia; somatosensory perception; perception thresholds; diffuse noxious inhibitory controls DNIC ; central hyperexcitability; tourniquet test; cold-pressor test.;

    Sammanfattning : The underlying mechanisms maintaining long-term pain localised to musculoskeletal structures and joints are not infrequently unknown. In routine clinical work with such patients insufficient attention has been paid to phenomena indicating altered excitability of the central nervous system (CNS). LÄS MER

  4. 3. Combined oral contraceptives : impact on the vulvar vestibular mucosa and pain mechanisms

    Författare :Ulrika Johannesson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :combined oral contraceptives; quantitative sensory testing; pain thresholds; DNIC; endogenous; pain modulation; provoked vestibulodynia; vulvar vestibulitis syndrome; morphology; vulvar mucosa; steroid receptors;

    Sammanfattning : Objective: The main aim of this thesis was to study the impact of combined oral contraceptives (COC) on the vulvar vestibular mucosa and pain mechanisms; in healthy women and in women with provoked vestibulodynia (former vulvar vestibulitis syndrome). The somatosensory perception in the vulvar vestibular mucosa of healthy women was studied with the relation to COC. LÄS MER