Sökning: "diffuse gliomas"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden diffuse gliomas.

  1. 1. On the Surgical Management of Diffuse Low-Grade Gliomas in Adults

    Författare :Louise Carstam; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diffuse Low-Grade Gliomas; Surgery; IDH-mutation;

    Sammanfattning : Diffuse low-grade gliomas (dLGG) are rare, slow-growing, yet difficult-to-treat brain tumors that typically affect young to middle-aged adults. The aim of the thesis has been to identify factors affecting management and outcome in terms of symptoms and primarily survival for patients with dLGG. LÄS MER

  3. 2. DNA methylation profiling of CNS tumors; implications for clinical diagnostics

    Författare :Sandra Ferreyra Vega; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Central nervous system tumors; DNA methylation; clinical diagnostics; diffuse gliomas; meningiomas; heterogeneity;

    Sammanfattning : Diffuse gliomas and meningiomas are the most common primary tumors of the central nervous system (CNS) in adults and these tumors cause significant morbidity and mortality worldwide. Deregulation of the epigenetic mechanisms, e.g. LÄS MER

  4. 3. Cognitive Deficits Reflecting Diffuse and Focal Brain Lesions Caused by Slow Growing Brain Tumors - Low-grade Gliomas

    Författare :Lena Ek; Ove Almkvist; Anja Smits; Hans Samuelsson; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Cognition; low-grade glioma; brain tumor; diffuse brain injury; neuropsychological tests; Psychology; Psykologi; Psychology; psykologi;

    Sammanfattning : The overall purpose was to characterize the impact that low-grade glioma (LGG) – a type of slowly growing brain tumor – has on cognitive functions. Paper I was an in-depth analysis of cognitive dysfunction of patients with histological proven LGG. LÄS MER

  5. 4. Significance of white matter anatomy in interpreting features and behaviour of low-grade gliomas and implications for surgical treatment

    Författare :Francesco Latini; Mats Ryttlefors; Lorenzo Bello; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; White matter; Cerebral gliomas; DTI; Brain-Grid; Brain mapping; Human connectome project; Anatomi; Human Anatomy; Oncology; Onkologi; Neurokirurgi; Neurosurgery; Radiology; Radiologi; Neurology; Neurologi;

    Sammanfattning : Diffuse gliomas are extremely heterogeneous tumours characterized by slow growth but extensive infiltration. Their kinetic features reflect the complex interaction over time with the surrounding brain, influencing treatment planning and outcome. LÄS MER

  7. 5. lmproving diagnosis of central nervous system tumours using genetic and epigenetic tools

    Författare :Thomas Olsson Bontell; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Histopathology; DNA methylation profiling; DNA methylation-based classification; Diffuse lower grade-glioma; Genomic analysis; Molecular biomarkers; Pediatric glioma;

    Sammanfattning : Brain tumor diagnostics has traditionally been based on histopathology stains. The introduction of immunohistochemistry stains resulted in improved ability to classify these often devastating tumors. The understanding of molecular markers in central nervous system tumors has improved substantially in recent decades. LÄS MER