Sökning: "diffferentiation"

Hittade 1 avhandling innehållade ordet diffferentiation.

1. 1. The role of the leukemia-associated ETO homologue repressors in hematopoiesis

   Författare :André Olsson; Avdelningen för hematologi och transfusionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MTGR1; ETO; MTG16; AML1-ETO; hematopoiesis; leukemia; diffferentiation; extracellular fluids; Haematology; Medicin människa och djur ; extracellulära vätskor; Hematologi; Medicine human and vertebrates ;

   Sammanfattning : The fusion protein AML1-ETO is observed in acute myeloid patients with the chromosomal translocation t(8;21). Cells with this chimeric protein have impaired granulocytic and erythroid differentiation with accumulation of myeloblasts. The transcriptional co-repressor ETO (Eight Twenty One) was identified from the cloning of AML1-ETO. LÄS MER