Sökning: "diesters"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet diesters.

1. 1. Computational Protein Evolution : Modeling the Selectivity and Promiscuity of Engineered Enzymes

   Författare :Klaudia Szeler; Shina C. Lynn Kamerlin; Mikael Widersten; Maria Ramos; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; enzymes; kinetics; catalysis; density functional theory; empirical valence bond; diesters; evolution; promiscuity; Biokemi; Biochemistry;

   Sammanfattning : Enzymes are biological catalysts that significantly increase the rate of all biochemical reactions that take place within cells and are essential to maintain life. Many questions regarding their function remain unknown. LÄS MER

3. 2. Studies on the synthesis of nucleotide analogues containing P-F and P-Se bonds

   Författare :Martin Bollmark; Janusz Rachon; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

   Sammanfattning : In the present work, new synthetic approaches to the synthesis of nucleoside phosphorofluoridate and phosphorofluoridothioate diesters have been developed. These procedures involve either oxidative transformation of the corresponding H-phosphonate or H-phosphonothioate diesters in the presence of fluoride anion or iodine-promoted desulfurization of phosphorothioate or phosphorodithioate diesters in the presence of fluoride anion. LÄS MER

4. 3. Phthalates in landfill leachates : a signature of their degradation: Analytical aspects & toxicological considerations

   Författare :Susanne Jonsson; Bo Svensson; Linköpings universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; INTERDISCIPLINARY RESEARCH AREAS; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN;

   Sammanfattning : Phthalic acid diesters comprise a large group of organic compounds that are used to manufacture a variety of products all over the world, and this has raised concerns about the fate of these compounds in the environment. The diester-containing products often end up in landfills, where they are degraded by various micro-organisms, which gives rise to transient intermediates such as phthalic acid monoesters and ortho-phthalic acid. LÄS MER

5. 4. Studies on nucleoside H-phosphonoselenoate chemistry and chalcogen exchange reaction between P(V) and P(III) compounds

   Författare :Martin Kullberg; Jacek Stawinski; Wojciech Markiewicz; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Phosphorus chemistry; H-phosphonate; H-phosphonoselenoate; nucleotide analogues; selenization; selenium transfer; phosphoroselenoate; Organic chemistry; Organisk kemi;

   Sammanfattning : In this thesis, the chemistry of compounds containing P-Se bonds has been studied. As a new addition to this class of compounds, H-phosphonoselenoate monoesters, have been introduced and two synthetic pathways for their preparation have been developed. LÄS MER

7. 5. Studies on Oxidative Couplings in H-Phosphonate Chemistry

   Författare :Johan Nilsson; Jacek Stawinski; Esther Kuyl-Yeheskiely; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; oxidative coupling; H-phosphonate; H-phosphonothioate; organisk kemi; Organic chemistry; Organisk kemi;

   Sammanfattning : In this thesis oxidative coupling of H-phosphonate and H phosphonothioate diesters with different alcohols and amines are presented. Since the reactions with alcohols previously have been particularly unfavourable due to competing side reactions, a modified protocol leading to high coupling yields of structurally diverse hydroxylic components was developed. LÄS MER