Sökning: "diastereoselectivity"

Visar resultat 16 - 20 av 30 avhandlingar innehållade ordet diastereoselectivity.

  1. 16. Palladium(0)-Catalyzed Synthesis of Spirocycles and Supercritical Chemistry using a Resistively Heated Flow Reactor

    Författare :Ahmed Adeyemi; Mats Larhed; Luke R. Odell; Kenneth Wärnmark; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Continuous Flow; Resistive heating; Supercritical fluids; high-temperature synthesis; Mizoroki-Heck reaction; Spirooxindoles; Spiroethers; Spirobenzofuranes; Unnatural Amino Acids;

    Sammanfattning : This doctoral thesis focusses on an effective and selective approach to the synthesis of spirocycles using palladium(0)-catalyzed Mizoroki-Heck reactions. In addition, selective and efficient chemistry was highlighted by the design and evaluation of a novel resistively heated system for continuous flow (CF) synthesis for high-temperature and high-pressure applications. LÄS MER

  3. 17. Silaborations of Unsaturated Compounds

    Författare :Martin Gerdin; Christina Moberg; Kálmán Szabó; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allylboration; bismetallation; boron; carbocyclization; catalysis; 1; 3-diene; enantioselective; 1; 6-enyne; interelement; N-heterocyclic carbene; nickel; palladium; phosphine; phosphoramidite; platinum; reaction mechanism; silaboration; silicon; silylborane; stereoselective; Chemistry; Kemi;

    Sammanfattning : This thesis deals with the development of transition metal-catalyzed silaborations of 1,3-dienes and 1,6-enynes. The first part of the thesis describes the development of the enantioselective 1,4-silaboration of 1,3-cyclohexadiene. A number of chiral metal-ligand complexes were evaluated. LÄS MER

  4. 18. Palladium(II)-Catalyzed Oxidative Cyclization Strategies : Selective Formation of New C-C and C-N Bonds

    Författare :Andreas K. Å. Persson; Jan-Erling Bäckvall; Matthew Sigman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Carbocyclization; Palladium Catalysis; Oxidation; Cyclization; Enallenes; Aza-Enallenes; Dienallenes; Allenylation; Oxazolidinones; Biomimetic; Arylation; Borylation; Transmetallation; organisk kemi; Organic Chemistry;

    Sammanfattning : The main focus of this thesis has been directed towards preparation and oxidative carbocyclization of en-, dien- and aza-enallenes.In the first part of this thesis, a stereoselective oxidative carbocyclization of dienallenes was realized. LÄS MER

  5. 19. Chemoenzymatic methods for the syntesis of pine sawfly sex peromones

    Författare :Helen Edlund; KTH; []
    Nyckelord :pheromone syntheses; pine sawfly; diprion pini; gilpinia pallida; kenetic resolution; water activity;

    Sammanfattning : This thesis describes the syntheses of pine sawfly sexpheromones via two synthetic routes. The preparation ofenantiomerically pure building blocks for these is alsodescribed.Lipase catalysed methods were developed for either theresolution or desymmetrisation of building blocks. LÄS MER

  7. 20. Deracemization of Functionalized Alcohols via Combined Ruthenium and Enzyme Catalysis

    Författare :Ann-Britt L. Fransson; Jan-Erling Bäckvall; Hans-Erik Högberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Sammanfattning : The major part of this thesis describes the synthesis of enantiopure alcohols and diols by combining ruthenium-catalyzed racemization or epimerization and lipase-catalyzed asymmetric transformations. A minor part of this thesis is focused on ruthenium-catalyzed redox reactions for transfer hydrogenation of 1,3-cycloalkanediketones. LÄS MER