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Visar resultat 1 - 5 av 154 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Proteomic Analysis of Urinary Bladder Cancer : Aiming for Novel Biomarkers

   Författare :Mårten Lindén; Per-Uno Malmström; Ulrika Segersten; Sara Bergström Lind; Lars Egevad; Uppsala universitet; []
   Nyckelord :urine; APOE; FGB; GAL1; LRG1; POLR1E; SERPINA1; STMN1; TOP2A; biomarker; diagnostic biomarker; prognostic biomarker; predictive biomarker; mass spectrometry; western blot; dot blot; immunohistochemistry; IHC; tissue microarray; TMA; urothelium; antibody; antibody-based; urinblåsecancer; biomarkör; diagnos; prognos; urin; proteomik; masspektrometri; immunohistokemi; antikroppar; Molecular Biology; Molekylärbiologi; Molekylär medicin; Molecular Medicine;

   Sammanfattning : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. LÄS MER

3. 2. Type IV collagen in breast and colorectal cancer : a potential biomarker of metastatic disease

   Författare :Moa Lindgren; Hanna Nyström; Ingrid Ljuslinder; Malin Sund; Kristian Pietras; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; colorectal liver metastases; breast cancer; breast cancer metastases; tumor marker; biomarker; stroma; type IV collagen;

   Sammanfattning : Background: Metastatic colorectal cancer (mCRC) and metastatic breast cancer (mBC) are two leading causes of cancer-related mortality worldwide. Early detection of metastatic disease is critical, and sensitive, easily accessed and cost-effective biomarkers that can diagnose mBC and mCRC at an early stage would have high clinical value. LÄS MER

4. 3. On the prognostic value of Heparin-binding protein in Sepsis

   Författare :Jonas Tverring; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sepsis; Biomarker; Heparin-binding protein HBP ; Diagnostic accuracy; added value;

   Sammanfattning : Sepsis causes major morbidity and mortality worldwide. There is wide consensus that biomarkers have an important role in sepsis research and patient care. Heparin-binding protein (HBP) is a neutrophil-derived, proinflammatory and vascular permeability-inducing protein and a promising novel sepsis biomarker. LÄS MER

5. 4. Measuring distal airspace dimensions with nanoparticles. Initial development of a diagnostic method

   Författare :H Laura Aaltonen; Malmö Diagnostisk radiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nanoparticles; COPD; AiDA; biomarker;

   Sammanfattning : Chronic obstructive pulmonary disease (COPD) consists of emphysema and bronchial disease. The pulmonary function tests currently used to diagnose COPD have poor sensitivity for early disease. This may delay diagnosis and lead to a poorer prognosis compared to establishing the diagnosis at an earlier stage. LÄS MER

7. 5. Clinical studies of RNA as a prognostic and diagnostic marker for disease

   Författare :Helena Isaksson; Torbjörn Nilsson; Bengt Sorbe; Gisela Helenius; Ola Hammarsten; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gene expression; ovarian cancer; hypercalprotectinaemia; hyperzincaemia; ischemia; biomarker;

   Sammanfattning : Technologies for RNA detection are evolving rapidly and gives an op-portunity for discovery of new markers for early detection of complex diseases. Today in clinical work we rely on signs and symptoms in com-bination with the measurement of protein levels for diagnosis. LÄS MER