Sökning: "diagnostic biomarker"

Visar resultat 1 - 5 av 129 avhandlingar innehållade orden diagnostic biomarker.

  1. 1. Proteomic Analysis of Urinary Bladder Cancer : Aiming for Novel Biomarkers

    Författare :Mårten Lindén; Per-Uno Malmström; Ulrika Segersten; Sara Bergström Lind; Lars Egevad; Uppsala universitet; []
    Nyckelord :urine; APOE; FGB; GAL1; LRG1; POLR1E; SERPINA1; STMN1; TOP2A; biomarker; diagnostic biomarker; prognostic biomarker; predictive biomarker; mass spectrometry; western blot; dot blot; immunohistochemistry; IHC; tissue microarray; TMA; urothelium; antibody; antibody-based; urinblåsecancer; biomarkör; diagnos; prognos; urin; proteomik; masspektrometri; immunohistokemi; antikroppar; Molecular Biology; Molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. LÄS MER

  2. 2. On the prognostic value of Heparin-binding protein in Sepsis

    Författare :Jonas Tverring; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sepsis; Biomarker; Heparin-binding protein HBP ; Diagnostic accuracy; added value;

    Sammanfattning : Sepsis causes major morbidity and mortality worldwide. There is wide consensus that biomarkers have an important role in sepsis research and patient care. Heparin-binding protein (HBP) is a neutrophil-derived, proinflammatory and vascular permeability-inducing protein and a promising novel sepsis biomarker. LÄS MER

  3. 3. Measuring distal airspace dimensions with nanoparticles. Initial development of a diagnostic method

    Författare :H Laura Aaltonen; Malmö Diagnostisk radiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nanoparticles; COPD; AiDA; biomarker;

    Sammanfattning : Chronic obstructive pulmonary disease (COPD) consists of emphysema and bronchial disease. The pulmonary function tests currently used to diagnose COPD have poor sensitivity for early disease. This may delay diagnosis and lead to a poorer prognosis compared to establishing the diagnosis at an earlier stage. LÄS MER

  4. 4. Clinical studies of RNA as a prognostic and diagnostic marker for disease

    Författare :Helena Isaksson; Torbjörn Nilsson; Bengt Sorbe; Gisela Helenius; Ola Hammarsten; Örebro universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gene expression; ovarian cancer; hypercalprotectinaemia; hyperzincaemia; ischemia; biomarker;

    Sammanfattning : Technologies for RNA detection are evolving rapidly and gives an op-portunity for discovery of new markers for early detection of complex diseases. Today in clinical work we rely on signs and symptoms in com-bination with the measurement of protein levels for diagnosis. LÄS MER

  5. 5. CSF biomarkers reflecting beta-amyloid and axonal pathology in Alzheimer's disease and related conditions

    Författare :Niklas Mattsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Alzheimer s disease; biomarker; cerebrospinal fluid; beta-amyloid; axonal; Niemann-Pick type C; neuroborreliosis;

    Sammanfattning : Cerebrospinal fluid (CSF) biomarkers may be used to identify and monitor pathological processes in the central nervous system. CSF biomarkers in Alzheimer’s disease (AD) include β-amyloid 42 (Aβ42), total-tau (T-tau) and phosphorylated-tau (P-tau), reflecting brain amyloid, axonal and tangle pathology, respectively. LÄS MER