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Visar resultat 1 - 5 av 49 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Diabetic Vascular Complications & Inflammation - role of NFAT and TNFalpha

   Författare :Jenny Öhman; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular; hyperglycemia; osteopontin; NFAT; diabetes; retinopathy; TNF; UTP;

   Sammanfattning : Vascular complications of diabetes account for the majority of morbidity and mortality among diabetic patients. Large clinical trials have identified hyperglycemia as a risk factor in the development of diabetic vascular complications. LÄS MER

3. 2. NFAT signaling in chronic and acute inflammation - A novel target for the treatment of diabetic vascular complications and acute pancreatitis?

   Författare :Anna Zetterqvist; Diabetiska komplikationer; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NFAT; vascular; diabetes; inflammation; atherosclerosis; diabetic retinopathy; acute pancreatitis; osteopontin; VCAM-1; A-285222;

   Sammanfattning : Diabetic patients suffer from macro- and microvascular complications causing increased morbidity and mortality. How hyperglycemia provokes vascular damage remains unclear, but glucose is believed to fuel a harmful low-grade chronic inflammation of the vessel wall. LÄS MER

4. 3. Prevention of foot ulcers in patients with diabetes mellitus

   Författare :Magdalena Annersten Gershater; Malmö högskola; []
   Nyckelord :amputation; complications; diabetes mellitus; diabetic foot ulcers; documentation; education; healing; home care; neuropathy; nursing; nursing process; peripheral vascular disease; pressure ulcer; prevention; RCT;

   Sammanfattning : Amputation in patients with diabetes mellitus preceded by a foot ulcer is a serious complication. Patients with the highest risk of developing a foot ulcer are often found in home nursing settings. LÄS MER

5. 4. Role of NFAT (nuclear factor of activated T cells) in vascular smooth muscle

   Författare :Lisa Berglund; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular smooth muscle; proliferation; A-285222; osteopontin; AIF-1; diabetes; vascular disease; calcium; glucose; NFAT;

   Sammanfattning : The calcium-dependent transcription factor NFAT was first described as a key player in immune cell regulation. Since then, NFAT signaling has been shown to be crucial for normal vascular development during embryogenesis. LÄS MER

7. 5. Semicarbazide-sensitive Amine Oxidase (SSAO) – Regulation and Involvement in Blood Vessel Damage with Special Regard to Diabetes : A Study on Mice Overexpressing Human SSAO

   Författare :Camilla Göktürk; Lars Oreland; Karin Forsberg-Nilsson; Dan Larhammar; Peter Yu; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; amine oxidases; VAP-1; vascular complications; diabetes; blood pressure; Farmakologi; Pharmacological research; Farmakologisk forskning;

   Sammanfattning : Semicarbazide-sensitive amine oxidase (SSAO, EC 1.4.3.6) belongs to a family of copper-containing amine oxidases. LÄS MER