Sökning: "diabetes nephropathy lipid"

Hittade 3 avhandlingar innehållade orden diabetes nephropathy lipid.

  1. 1. Macro- and microvascular complications of diabetes: Studies on NFAT (Nuclear Factor of Activated T-cells) as a novel target for the treatment of atherosclerosis and vascular dysfunction in diabetes

    Författare :Fabiana Blanco; Diabetiska komplikationer; []
    Nyckelord :NFAT; VSMCs; Diabetes; Hyperglycemia; Aterosclerosis; Diabetic retinopathy; Oxidative stress;

    Sammanfattning : Diabetes is associated with devastating chronic complications including coronary heart disease and stroke (macrovascular complications) as well as microvascular disorders leading to damage of the small vessels and the development of retinopathy, nephropathy and neuropathy. The underlying pathogenesis is not clear, but hyperglycemia has been identified as an important risk factor. LÄS MER

  3. 2. Treatment of cardiovascular risk factors in type 2 diabetes : time trends and clinical practice

    Författare :Eva Fhärm; Olov Rolandsson; Eva Johansson; Lars Weinehall; Carl-Johan Östgren; Umeå universitet; []
    Nyckelord :diabetes mellitus; cardiovascular disease; effectiveness; epidemiology; guideline adherence; primary health care; risk factor;

    Sammanfattning : Objectives Patients with type 2 diabetes are at much greater risk of developing cardiovascular diseases (CVD), including coronary heart disease (CHD), compared to non-diabetics. The lowering of glucose, blood pressure, and plasma lipid levels has been shown to reduce CHD risk, and treatment goals for these risk factors are now part of clinical practice guidelines. LÄS MER

  4. 3. Vascular endothelial growth factor B-role in metabolism, lipotoxicity and disease

    Författare :Annika Mehlem; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Vascular Endothelial Growth Factor B (VEGF-B) was previously shown to control lipid uptake from the bloodstream via the endothelium into tissue cells, and when ablating Vegfb, intra-tissue lipid accumulation was reduced. However, very little is known regarding the metabolic role of VEGF-B in physiologic, or pathophysiologic conditions. LÄS MER